GEO DataSets

(Submitter supplied) Here we analyze the transcriptomic profile of Streptococcus pneumoniae D39 Dspd_1448::KanrpsL (IU10991) vs Streptcococcus penumoiae D39 wt (IU1781) under anaerobic growth condition in BHI growth media

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24384

6 Samples

Download data: TXT

(Submitter supplied) The goal of this study is to obtain a genomic view of the Fur regulatory network under both iron replete and iron deficient conditions in Bacillus subtilis using ChIP-seq. Besides the known Fur target sites, 70 putative DNA binding sites were identified, and the vast majority had higher occupancy under iron sufficient conditions. In addition,we discovered a role for catechol degradation in bacillibactin metabolism, and provided evidence that catechol 2,3-dioxygenase can detoxify endogenously produced catechol substrates in addition to its more widely studied role in biodegradation of environmental aromatic compounds and pollutants.

Organism:

Bacillus subtilis

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL24109

5 Samples

Download data: WIG

(Submitter supplied) Post-transcriptional gene regulation often involves RNA-binding proteins that modulate mRNA translation and/or stability either directly through protein-RNA interactions or indirectly by facilitating the annealing of small regulatory RNAs (sRNAs). The human pathogen Streptococcus pneumoniae D39 (pneumococcus) does not encode in its genome any homologs to RNA-binding proteins known to be involved in promoting sRNA stability and function, such as Hfq or ProQ, even though it contains genes for at least 112 sRNAs. more...

Organism:

Streptococcus pneumoniae D39

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL22880

6 Samples

Download data: XLS

(Submitter supplied) By using the transcriptomic approach, we have elucidated the effect of Ni2+ on the global gene expression of S. pneumoniae D39 by identifying several differentially expressed genes/operons in the presence of a high extracellular concentration of Ni2+. The genes belonging to the AdcR regulon (adcRCBA, adcAII-phtD, phtA, phtB and phtE) and the PsaR regulon (pcpA, prtA and psaBCA) were highly upregulated in the presence of Ni2+. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

4 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type to D39 ΔadcR grown in CDM with 0.3 mM Ni2+

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grownin CDM with 0.5 mM Ni2+ to grown in CDM with 0 mM Ni2+

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Iron-sulphur (Fe-S) clusters are ensembles of iron and sulphide centres. They are found in all life forms and are important components of many enzymes involved in diverse cellular processes, including respiration, DNA synthesis or gene regulation. However, the increase in oxygen after the emergence of oxygenic photosynthesis created a threat to Fe–S proteins and, consequently, to the organisms relying on them. more...

Organism:

Cereibacter sphaeroides 2.4.1

Type:

Expression profiling by array

Platform:

GPL15457

2 Samples

Download data: TXT

(Submitter supplied) In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39 to methionine. Transcriptome comparison of the S. pneumoniae D39 wild-type grown in chemically defined medium (CDM) with 0mM to 10mM methionine revealed the elevated expression of various genes/operons involved in methionine synthesis and transport (fhs, folD, gshT, metA, metB, metEF, metQ, tcyB, spd-0150, spd-0431, and spd-0618). more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) By comparing the transcriptome of Streptococcus pneumoniae wild-type D39 (serotype 2) to an isogenic strain overexpressing the response regulator of Two-Component System 7 (SPD_0158), we identified the regulon of the two-component system. In total 20 and 24 genes were considered up- and downregulated, respectively. 11 of the upregulated genes encode for proteins involved in host-glycan metabolism, while 7 encode proteins involved in carbohydrate metabolism. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26778

8 Samples

Download data: TXT

(Submitter supplied) The maltose regulon (mal regulon) has previously been shown to consist of the mal gene cluster (malQP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study, we have further elucidated the complete mal regulon in S. pneumoniae D39 using microarray analyses and β-galactosidase assays. In addition to the mal gene cluster, the complete mal regulon of S. pneumoniae D39 consists of a pullulanase (PulA), a glucosidase (DexB), a glucokinase (RokB), a PTS component (PtsG) and an amylase (AmyA2). more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

7 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grown in MM17 (0.5 % (w/v) Maltose + M17) to grown in GM17 (0.5 % (w/v) Glucose + M17).

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

3 Samples

Download data: TXT

(Submitter supplied) Transcriptome Comparison of the Streptococcus pneumoniae D39 ΔmalR mutant to D39 wild type grown in GM17 (0.5 % (w/v) Glucose + M17) medium.

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild-type grown in MM17 (0.5 % (w/v) Maltose + M17) medium

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

2 Samples

Download data: TXT

(Submitter supplied) Streptococcus pyogenes (Group A Strep, GAS) is a serious human pathogen with the ability to colonize mucosal surfaces such as the nasopharynx and vaginal tract, often leading to infections such as pharyngitis and vulvovaginitis. We present genome-wide RNASeq data showing the transcriptomic changes GAS undergoes during vaginal colonization. These data reveal that the regulon controlled by MtsR, a master metal regulator, is activated during vaginal colonization. more...

Organism:

Streptococcus pyogenes

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20656

6 Samples

Download data: GTF, TXT

(Submitter supplied) We determined genes that directly or indirectly regulated by CatR (or PerR), and hydrogen peroxide regulon in Streptomyces coelicolor.

Organism:

Streptomyces coelicolor

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27129

6 Samples

Download data: CSV

(Submitter supplied) Transcriptome Comparison of the Streptococcus pneumoniae D39 wild-type grown in CDM with 0 mM to 10mM Niacin

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL22631

2 Samples

Download data: TXT

(Submitter supplied) Transcriptome comparison of the Streptococcus pneumoniae D39 ΔnaiR to D39 wild type grown in CDM

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL22631

2 Samples

Download data: TXT

(Submitter supplied) Bacterial cells often modulate their transcriptional profiles in response to the changes in iron availability. Ferric uptake regulator (Fur), as a global iron biosensor, plays a central role in maintaining iron homeostasis in Bacillus subtilis. Here we utilized a high affinity Fe2+ efflux transporter, Listeria monocytogenes FrvA, as an inducible genetic tool to deplete intracellular iron. We then characterized the responses of the Fur, FsrA, and PerR regulons as cells transition from iron sufficiency to deficiency. more...

Organism:

Bacillus subtilis

Type:

Expression profiling by array

Platform:

GPL13726

8 Samples

Download data: GPR

(Submitter supplied) Before and after anaerobic Fe(II) shocked WT and ∆bqsR of late stationary phase P. aeruginosa PA14 strains Associated publication: Kreamer NN, Costa F, Newman DK. 2015. The ferrous iron-responsive BqsRS two-component system activates genes that promote cationic stress tolerance. mBio 6(1):e02549-14. doi:10.1128/mBio.02549-14.

Organism:

Pseudomonas aeruginosa

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18287

12 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Geobacter sulfurreducens PCA

Type:

Expression profiling by genome tiling array; Genome binding/occupancy profiling by genome tiling array

Platform:

GPL9112

16 Samples

Download data: GFF, PAIR