GEO DataSets

(Submitter supplied) To study the effect of dietary restriction on killifish, we generated transcriptomes (RNA-seq) for the livers and brains of male and female killifish that had been subjected to different dietary treatements. 

Organism:

Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32658

32 Samples

Download data: CSV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL33195 GPL30852

51 Samples

Download data: CSV

(Submitter supplied) Classical evolutionary theories propose tradeoffs between reproduction, damage repair, and lifespan. However, the specific role of the germline in shaping vertebrate aging remains largely unknown. Here, we use the turquoise killifish (N. furzeri) to genetically arrest germline differentiation at discrete stages, and examine how different ‘flavors’ of infertility impact life-history. We first constructed a comprehensive single-cell gonadal atlas, providing cell-type-specific markers for downstream phenotypic analysis. more...

Organism:

Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33195

28 Samples

Download data: CSV

(Submitter supplied) This approach was used to increase the continuity of the killifish genome, and assess the relative distance of specific genes from the sex locus.

Organism:

Nothobranchius furzeri

Type:

Other

Platform:

GPL30852

2 Samples

Download data: FASTA, HIC

(Submitter supplied) In many vertebrate species, age at maturity is proportional to organismal lifespan. A number of theories have attempted to provide a conceptual framework for this fascinating apparent co-evolution. The ‘disposable soma’ theory predicts that costly resources that are invested in germline preservation come at the expense of repairing age-related somatic damage. On the other hand, classical experiments in C. more...

Organism:

Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30852

23 Samples

Download data: CSV

(Submitter supplied) A vast body of studies is available that describes age-dependent gene expression in relationship to aging in a number of different model species. These data were obtained from animals kept in conditions with reduced environmental challenges, abundant food and deprivation of natural sensory stimulation. Here we compared wild- and captive-aging in the short-lived turquoise killifish (Nothobranchius furzeri). more...

Organism:

Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19871

24 Samples

Download data: XLS

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Austrofundulus limnaeus; Aphyosemion australe; Iconisemion striatum; Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

8 related Platforms

175 Samples

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(Submitter supplied) We evaluate the global chromatin changes that occur during the developmental progression and development-to-diapause transition in a closely related set of killifish species.

Organism:

Austrofundulus limnaeus; Iconisemion striatum; Aphyosemion australe; Nothobranchius furzeri

Type:

Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms

30 Samples

Download data: TXT

(Submitter supplied) We evaluate the global gene expression changes that occur during a stage-matched developmental window in a closely related set of killifish species.

Organism:

Iconisemion striatum; Aphyosemion australe; Nothobranchius furzeri

Type:

Expression profiling by high throughput sequencing

4 related Platforms

145 Samples

Download data: CSV