GEO DataSets

(Submitter supplied) Streptococcus gallolyticus sp. gallolyticus (SGG) is a gut pathobiont involved in the development of colorectal cancer (CRC). To decipher SGG contribution in tumor initiation and/or acceleration respectively, a global transcriptome was performed in normal colonic cells (FHC) and in tumoral colonic cells (HT29). To identify SGG-specific alterations, we chose the phylogenetically closest relative, Streptococcus gallolyticus subsp. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16791

18 Samples

Download data: TXT

(Submitter supplied) Bacteriocins are natural antimicrobial peptides produced by a bacterium to kill closely related competitors. Streptococcus gallolyticus subsp. gallolyticus (Sgg) UCN34 produces a two-component bacteriocin named gallocin to colonize the gut by killing resident enterococci. In the present work, we investigated how gallocin was regulated by deleting individually three genes present in the locus and encoding potentially an inducing peptide (gsp), a histidine kinase (ghk) and a LytTR-containing response regulator (grr). more...

Organism:

Streptococcus gallolyticus UCN34

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28370

12 Samples

Download data: TXT

(Submitter supplied) The opportunistic pathogen Streptococcus gallolyticus is one of the few intestinal bacteria that has been consistently linked to colorectal cancer (CRC). This study aimed to identify S. gallolyticus-induced pathways that could on the long-term add to CRC progression. Transcription profiling of S. gallolyticus-exposed CRC-cells revealed the persistent induction of enzymes involved in biotransformation pathways. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL5175

8 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Streptococcus gallolyticus subsp. gallolyticus

Type:

Expression profiling by array

Platform:

GPL23196

24 Samples

Download data: TXT

(Submitter supplied) Background: Streptococcus gallolyticus subsp. gallolyticus (S. gallolyticus) is a pathogen of infective endocarditis. It was observed previously that this bacterium survives longer in macrophages than other species and the phagocytic uptake by and survival in THP-1 macrophages is strain-dependent. Methods: The phagocytosis assay was performed with THP-1 macrophages. S. gallolyticus specific whole genome microarrays were used for transcriptome analysis. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) Background: Streptococcus gallolyticus subsp. gallolyticus (S. gallolyticus) is a pathogen of infective endocarditis. It was observed previously that this bacterium survives longer in macrophages than other species and the phagocytic uptake by and survival in THP-1 macrophages is strain-dependent. Methods: The phagocytosis assay was performed with THP-1 macrophages. S. gallolyticus specific whole genome microarrays were used for transcriptome analysis. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) Background: Streptococcus gallolyticus subsp. gallolyticus (S. gallolyticus) is a pathogen of infective endocarditis. It was observed previously that this bacterium survives longer in macrophages than other species and the phagocytic uptake by and survival in THP-1 macrophages is strain-dependent. Methods: The phagocytosis assay was performed with THP-1 macrophages. S. gallolyticus specific whole genome microarrays were used for transcriptome analysis. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) Background: Streptococcus gallolyticus subsp. gallolyticus (S. gallolyticus) is a pathogen of infective endocarditis. It was observed previously that this bacterium survives longer in macrophages than other species and the phagocytic uptake by and survival in THP-1 macrophages is strain-dependent. Methods: The phagocytosis assay was performed with THP-1 macrophages. S. gallolyticus specific whole genome microarrays were used for transcriptome analysis. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069; Streptococcus gallolyticus subsp. gallolyticus; Streptococcus gallolyticus UCN34; Streptococcus gallolyticus subsp. gallolyticus DSM 16831

Type:

Expression profiling by array

Platform:

GPL23196

24 Samples

Download data: TXT

(Submitter supplied) Streptococcus gallolyticus subsp. gallolyticus is a commensal of the human gastrointestinal tract and a pathogen of infective endocarditis and other biofilm-associated infections with exposed collagen. Therefore, this study focuses on the characterization of the biofilm formation and collagen adhesion of S. gallolyticus subsp. gallolyticus under different conditions. It has been observed that lysozyme triggers biofilm formation divergently in the analyzed S. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus; Streptococcus gallolyticus UCN34

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) Streptococcus gallolyticus subsp. gallolyticus is a commensal of the human gastrointestinal tract and a pathogen of infective endocarditis and other biofilm-associated infections with exposed collagen. Therefore, this study focuses on the characterization of the biofilm formation and collagen adhesion of S. gallolyticus subsp. gallolyticus under different conditions. It has been observed that lysozyme triggers biofilm formation divergently in the analyzed S. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus; Streptococcus gallolyticus subsp. gallolyticus DSM 16831

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) Streptococcus gallolyticus subsp. gallolyticus is a commensal of the human gastrointestinal tract and a pathogen of infective endocarditis and other biofilm-associated infections with exposed collagen. Therefore, this study focuses on the characterization of the biofilm formation and collagen adhesion of S. gallolyticus subsp. gallolyticus under different conditions. It has been observed that lysozyme triggers biofilm formation divergently in the analyzed S. more...

Organism:

Streptococcus gallolyticus UCN34; Streptococcus gallolyticus subsp. gallolyticus

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT

(Submitter supplied) Streptococcus gallolyticus subsp. gallolyticus is a commensal of the human gastrointestinal tract and a pathogen of infective endocarditis and other biofilm-associated infections with exposed collagen. Therefore, this study focuses on the characterization of the biofilm formation and collagen adhesion of S. gallolyticus subsp. gallolyticus under different conditions. It has been observed that lysozyme triggers biofilm formation divergently in the analyzed S. more...

Organism:

Streptococcus gallolyticus subsp. gallolyticus; Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069

Type:

Expression profiling by array

Platform:

GPL23196

6 Samples

Download data: TXT