GEO DataSets

Analysis of noncancerous hepatic tissues surrounding tumors from hepatocellular carcinoma (HCC) patients with and without venous metastasis. Results provide insight into the role of the hepatic microenvironment in HCC metastasis.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 2 disease state sets

Platform:

GPL1262

Series:

GSE5093

20 Samples

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(Submitter supplied) To determine the role of the hepatic microenvironment in HCC metastasis, we compared the gene expression profiles of 20 noncancerous surrounding hepatic tissues from two HCC patient groups, those with primary HCC together with venous metastasis which we termed a metastasis-inclined microenvironment (MIM) and those with HCC without detectable metastasis, which we termed a metastasis-averse microenvironment (MAM). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3091

Platform:

GPL1262

20 Samples

Download data

(Submitter supplied) In this study we investigated the miRNA expression profile of Hepatocellular carcinoma (HCC) specimens from radical resection. We developed a unique 20 miRNA signature that could significantly distinguish HCC venous metastasis from metastasis-free HCC. In contrast to HCC staging systems, this signature was capable of predicting survival and recurrence of HCC patients with multinodular or solitary tumors, including those with early-stage disease. more...

Organism:

Mus musculus; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL4700

482 Samples

Download data: GPR, TXT, XLS

(Submitter supplied) Progression of hepatocellular carcinoma (HCC) often leads to vascular invasion and intrahepatic metastasis, which correlate with recurrence after surgical treatment and poor prognosis. It is crucial to identify patients with a high risk of recurrence and develop more intensified or targeted treatment strategy to improve disease outcome.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

433 Samples

Download data: TXT

(Submitter supplied) We performed gene expression profiling of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and mixed type of combined HCC and CC (CHC). In comparison of the profiles, a novel class of HCC expressing CC-like traits was identified.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL571

90 Samples

Download data: CEL