Similar studies for GEO DataSets (Select 346) - GEO DataSets

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Items: 2

Select item 3461.

Serotonergic hallucinogen effect in somatosensory cortex

Effect of 5-HT2A seratonin receptor agonist (±)2,5-dimethoxy 4-iodoamphetamine (DOI) in somatosensory cortex. 129Sv mice injected with DOI (2 mg/kg or 10 mg/kg), 1 hour. Abnormal 5-HT2A receptor function implicated in depression and schizophrenia.

Organism:: Mus musculus

Type:: Expression profiling by array, log ratio, 2 dose sets

Platform:: GPL226
Series:: GSE138
7 Samples

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Accession:: GDS346

ID:: 346

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000001382.

Effect of serotonergic hallucinogen in mouse somatosensory cortex

(Submitter supplied) To investigate the gene program activated by serotonergic hallucinogens in mouse somatosensory cortex, the effects of the 5-HT2A agonist (±)2,5-dimethoxy 4-iodoamphetamine (DOI) on gene expression was studied. The 5-HT2A serotonin receptor is a member of the 5-HT2 receptor subfamily of G protein–coupled receptors. The 5-HT2A receptor is thought to modulate processes related to cognition, appetite, mood, anxiety, sleep, and sexual behavior. more...