GEO DataSets

Analysis of male and female flies of 5 wild-type laboratory strains. Results provide insight into the extent to which transcriptional variation is inherent in commonly used laboratory strains and the relationship of variation in gene expression to sexual dimorphism.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 gender, 5 strain sets

Platform:

GPL72

Series:

GSE9149

29 Samples

Download data: CEL

(Submitter supplied) Wild-type laboratory strains of model organisms are typically kept in isolation for many years, with the action of genetic drift and selection on mutational variation causing lineages to diverge with time. Natural populations from which such strains are established, show that gender-specific interactions in particular drive many aspects of sequence level and transcriptional level variation. Here, our goal was to identify genes that display transcriptional variation between laboratory strains of Drosophila melanogaster, and to explore evidence of gender-biased interactions underlying that variability. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS3639

Platform:

GPL72

29 Samples

Download data: CEL

(Submitter supplied) Background: Changes in gene regulation are thought to be crucial for the adaptation of organisms to their environment. Transcriptome analyses can be used to identify candidate genes for ecological adaptation, but can be complicated by variation in gene expression between tissues, sexes, or individuals. Here we use high-throughput RNA sequencing of a single Drosophila melanogaster tissue to detect brain-specific differences in gene expression between the sexes and between two populations, one from the ancestral species range in sub-Saharan Africa and one from the recently colonized species range in Europe. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13304

8 Samples

Download data: TXT

(Submitter supplied) Background: Differences in levels of gene expression among individuals are an important source of phenotypic variation within populations. Recent microarray studies have revealed that expression variation is abundant in many species, including Drosophila melanogaster. However, previous expression surveys in this species generally focused on a small number of laboratory strains established from derived populations. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3830

80 Samples

Download data: GPR

(Submitter supplied) A number of genes associated with sexual traits and reproduction evolve at the sequence level faster than the majority of genes coding for non-sex-related traits. Whole genome analyses allow this observation to be extended beyond the limited set of genes that have been studied thus far. We use cDNA microarrays to demonstrate that this pattern holds in Drosophila for the phenotype of gene expression as well, but in one sex only. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Datasets:

GDS438 GDS439 GDS440 GDS441

Platform:

GPL356

23 Samples

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(Submitter supplied) 5928 cDNAs from the Drosophila Gene Collection version 1.0 were amplified by PCR with universal primers and PCR products were confirmed by gel electrophoresis. Added to these was a set of 177 separately amplified controls, each of which was replicated from one to 16 times on the array. Clones for which the PCR product was absent, faint, the incorrect size, or showed multiple bands failed PCR quality control. more...

Organism:

Drosophila melanogaster

4 DataSets

3 Series

56 Samples

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Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 5 strain sets

Platform:

GPL356

Series:

GSE539

5 Samples

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Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 6 strain sets

Platform:

GPL356

Series:

GSE539

6 Samples

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Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 7 strain sets

Platform:

GPL356

Series:

GSE539

7 Samples

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Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 6 strain sets

Platform:

GPL356

Series:

GSE539

6 Samples

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(Submitter supplied) Differences in the selective pressures experienced by males and females are believed to be ubiquitous in dioecious organisms and are expected to result in the evolution of sexually antagonistic alleles, thereby driving the evolution of sexual dimorphism. Negative genetic correlation for fitness between the sexes has been documented, however, the identity, number and location of loci causing this relationship are unknown. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

120 Samples

Download data: CEL

(Submitter supplied) http://www.nature.com/ng/journal/v33/n2/abs/ng1086.html. Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition?the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...

Organism:

Drosophila simulans; Drosophila yakuba; Drosophila melanogaster

Type:

Expression profiling by array

5 related Platforms

48 Samples

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(Submitter supplied) Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition-the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...

Organism:

Drosophila simulans; Drosophila yakuba; Drosophila melanogaster

Type:

Expression profiling by array

Platforms:

GPL227 GPL228

26 Samples

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(Submitter supplied) Drosophila simulans blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster; Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster Samarkand blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

6 Samples

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(Submitter supplied) Drosophila melanogaster OregonR blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster Netherlands2 blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster CantonS blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila yakuba white prepupae vs. blue gut larvae Keywords: repeat sample

Organism:

Drosophila melanogaster; Drosophila yakuba

Type:

Expression profiling by array

Platform:

GPL227

4 Samples

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(Submitter supplied) The insulin signaling pathway is known to interact directly and indirectly with the sex determination regulatory hierarchy, playing a role in directing sexually dimorphic traits. To understand the degree to which the insulin signaling pathway contributes to sexually dimorphic gene expression in adult animals, we examined the effect of perturbation of the pathway on gene expression in male and female Drosophila. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17275

14 Samples

Download data: CSV