Similar studies for GEO DataSets (Select 3807) - GEO DataSets

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Items: 2

Select item 38071.

Sebacic acid supplemented diet effect on db/db liver

Analysis of livers of db/db animals fed a diet supplemented with sebacic acid (SA) for 6 weeks. SA supplementation improves fasting plasma glucose, HbA1c and glucose tolerance in this model of type 2 diabetes. Results provide insight into the mechanism of action of SA.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL6885
Series:: GSE21083
30 Samples

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DataSet

Accession:: GDS3807

ID:: 3807

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000210832.

Benefits of a 6 week supplementation of sebacic acid on a mouse model of type 2 diabetes (db/db mice)

(Submitter supplied) This study aimed at investigating the impact of chronic ingestion of sebacic acid (SA), a 10 carbons medium-chain dicarboxylic acid, on glycemic control in a mouse model of type 2 diabetes (db/db mice). Three groups of 15 mice were fed for 6 weeks either a chow diet (Ctrl), or a chow diet supplemented with 1.5% or 15% (SA1.5% and SA15% resp.) energy from SA. Fasting glycemia was measured once a week and HbA1c before and after supplementation. more...