GEO DataSets

Analysis of embryos from fertilization to 52h of development. Desiccation resistance develops 8-14h after egglaying and coincides with serosal cuticle formation. These, together with embryonic serosa results, provide insight into the molecular basis for the drought tolerance of A. gambiae embryos.

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array, transformed count, 20 time sets

Platform:

GPL1321

Series:

GSE15001

56 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array

Datasets:

GDS3843 GDS3844

Platform:

GPL1321

62 Samples

Download data: CEL

(Submitter supplied) In order to examine the gene expression in the course of mosquito embryogenesis, microarray assays were performed on staged A. gambiae embryos, from fertilization to 52 hours of development (which is close to hatching at ~50 hours post-fertilization). RNA was extracted from staged embryos roughly every three hours after fertilization, and then hybridized to the A. gambiae transcriptome microarray. Keywords: time-course

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array

Platform:

GPL1321

56 Samples

Download data: CEL

(Submitter supplied) Whole-genome transcriptome assays were performed with isolated serosa from A. gambiae embryos. These assays identified a large number of genes implicated in the production of the larval cuticle. In D. melanogaster, these genes are activated just once during embryogenesis, during late stages where they are used for the production of the larval cuticle. Evidence is presented that the serosal cells secrete a dedicated serosal cuticle, which protects A. more...

Organism:

Anopheles gambiae; Plasmodium falciparum

Type:

Expression profiling by array

Platform:

GPL1321

6 Samples

Download data: CEL

Analysis of isolated serosa or extracted embryos at 10.5 hours. Serosal cells secrete a dedicated serosal cuticle that protects embryos from desiccation. These results, together with array results for staged embryos, provide insight into molecular basis for the drought tolerance of A. gambiae.

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array, transformed count, 2 tissue sets

Platform:

GPL1321

Series:

GSE15001

6 Samples

Download data: CEL

(Submitter supplied) In spite of the many recent developments in the field of vector sialomics, the salivary glands of larvalmosquitoes have been largely unexplored. We used whole-transcriptome microarray analysis to create a gene-expression profile of the salivary gland tissue of fourth-instar Anopheles gambiae larvae, and compare it to the gene-expression profile of a matching group of whole larvae. We identified a total of 221 probes with expression values that were (a) significantly enriched in the salivary glands, and (b)sufficiently annotated as to allow the prediction of the presence/absence of signal peptides in their corresponding gene products. more...

Organism:

Anopheles gambiae; Plasmodium falciparum

Type:

Expression profiling by array

Platform:

GPL1321

6 Samples

Download data: CEL

(Submitter supplied) RNA-Seq was used for transcriptome sequencing of 0-12 hour embryos.

Organism:

Aedes aegypti

Type:

Expression profiling by high throughput sequencing

Platform:

GPL11087

4 Samples

Download data: BED

(Submitter supplied) Background: The mosquito Anopheles gambiae is a major vector of human malaria. Increasing evidence indicates that blood cells (hemocytes) comprise an essential arm of the mosquito innate immune response against both bacteria and malaria parasites. To further characterize the role of hemocytes in mosquito immunity, we undertook the first genome-wide transcriptomic analyses of adult female An. gambiae hemocytes following infection by two species of bacteria and a malaria parasite. more...

Organism:

Anopheles gambiae

Type:

Expression profiling by array

Platforms:

GPL8551 GPL8552 GPL8550

11 Samples

Download data

(Submitter supplied) With their genome sequenced, Anopheles gambiae mosquitoes now serve as a powerful tool for basic research in comparative, evolutionary and developmental biology. The knowledge generated by these studies is expected to reveal molecular targets for novel vector control and pathogen transmission blocking strategies. Comparisons of gene-expression profiles between adult male and nonblood-fed female Anopheles gambiae mosquitoes revealed that roughly 22% of the genes showed sex-dependent regulation. more...

Organism:

Anopheles gambiae; Plasmodium falciparum

Type:

Expression profiling by array

Platform:

GPL1321

36 Samples

Download data: CEL, CHP, EXP

(Submitter supplied) The earliest stage of animal development is controlled by maternally deposited mRNA transcripts and proteins. Once the zygote is able to transcribe its own genome, maternal transcripts are degraded, in a tightly regulated process known as the maternal to zygotic transition (MZT). While this process has been well-studied within model species, we have little knowledge of how the pools of maternal and zygotic transcripts evolve. more...

Organism:

Drosophila melanogaster; Drosophila yakuba; Drosophila ananassae; Drosophila erecta; Drosophila miranda; Drosophila sechellia; Drosophila simulans; Drosophila virilis; Drosophila mauritiana; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila willistoni; Drosophila persimilis; Drosophila santomea

Type:

Expression profiling by high throughput sequencing; Third-party reanalysis

14 related Platforms

119 Samples

Download data: TXT