GEO DataSets

Analysis of efferent ducts, epididymis, and vas deferens of CD1 males from embryonic day 14 to postnatal day 1. Proper development of these tissues is essential for fertility. Results provide insight into molecular mechanisms underlying tissue-specific regulation in organ morphogenesis.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 4 development stage, 3 tissue sets

Platform:

GPL1261

Series:

GSE22616

24 Samples

Download data: CEL

(Submitter supplied) The tissues of the male reproductive tract are characterized by distinct morphologies, ranging from highly coiled to un-coiled. Global gene expression profiles of the efferent ducts, epididymis, and vas deferens were generated from embryonic day 14.5 to postnatal day 1, the period when gross morphological changes are initiated and tissue-specific morphologies emerge. Expression profiles of homeobox genes, as potential regionalization factors, were examined. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3862

Platform:

GPL1261

24 Samples

Download data: CEL

(Submitter supplied) Mammalian spermatozoa acquire their fertilizing ability during epididymal transit. Gene expression patterns along the epididymis are established by specific transcription factor networks that coordinate region-specific functions. The epididymis is usually divided into 3 segments: caput, corpus, and cauda. The human epididymis anatomy does not allow clear distinction between these three segments. To determine to which extent gene expression is segmented along the human epididymis, transcriptome profiling was performed on 8 distinct epididymal regions from 3 donors. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23159

24 Samples

Download data: CEL

(Submitter supplied) Background - Mammalians gamete production takes place in the testis but when they exit this organ, although spermatozoa have a specialized and distinct morphology, they are immotile and infertile. It is only after their travel in the epididymis that sperm acquire their motility and fertility. Epididymis can be divided in three gross morphological regions, head (caput), body (corpus) and tail (cauda), containing a long and unique convoluted tubule connecting the testis to the vas deferens. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3729

96 Samples

Download data

(Submitter supplied) The role of estrogen and testosterone in the regulation of gene expression in the proximal reproductive tract is not completely understood. To address this question, mice were treated with testosterone or estradiol and RNA from the efferent ducts and caput epididymis was processed and hybridized to Affymetrix MOE 430 2.0 microarrays. Analysis of array output identified probe sets in each tissue with altered levels in hormone treated versus control animals. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

16 Samples

Download data: CEL, CHP