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Links from GEO DataSets

Items: 3

1.
Full record GDS5424

Commensal bacteria colonization effect on gnotobiotic model of food allergy: colonic epithelial cells

Analysis of intestinal epithelial cells (IECs) from gnotobiotic animals selectively colonized with Bacteroides uniformis or Clostridia. Results provide insight into the role of microbial interactions with IECs in protecting against sensitization to food allergens.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 protocol sets
Platform:
GPL6885
Series:
GSE60039
8 Samples
Download data
2.

Commensal bacteria protect against food allergen sensitization

(Submitter supplied) Analysis of colonic epithelial cell gene expression in germ-free, Bacteroides uniformis-colonized, and Clostridia-colonized gnotobiotic mice. Bacteria were isolated from our SPF mouse facility and were used to selectively colonize germ-free mice.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5424
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE60039
ID:
200060039
3.

Microbiota facilitates dietary heme-induced epithelial hyperproliferation and hyperplasia by breaking the mucus barrier

(Submitter supplied) Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia. Here we explore the possible causal role of the gut microbiota in heme-induced hyperproliferation. To this end, mice were fed a purified control or heme diet (0.5 μmol/g heme) with or without broad-spectrum antibiotics for 14 d. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11533
18 Samples
Download data: CEL
Series
Accession:
GSE40670
ID:
200040670
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