GEO DataSets

Analysis of glioma migration by comparing expression profiles of fast and slow invading C6 glial cells. Fast and slow cells separated using monolayer migration assay and by extent of migration of transplants in nude mice brains. Results provide insight into mechanisms underlying glioma invasion.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 cell type, 2 protocol sets

Platform:

GPL85

Series:

GSE1139

7 Samples

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(Submitter supplied) Identification of genes mediating glioma invasion promotes the understanding of glia motility and might result in biologically based therapeutic approaches. To evaluate migration mechanisms operating in vitro versus in vivo, we used C6 rat glioma cells for selecting highly migratory cells in a monolayer migration assay (C6) as well as in brains of nude mice (C6SPGFP), and analyzed in each paradigm the expression profiles of these "fast" cells versus those of the original "slow" cells. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS769

Platform:

GPL85

8 Samples

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(Submitter supplied) To investigate differences in gene expression after overexpression miR-218 in U251MG

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL14550

2 Samples

Download data: TXT

(Submitter supplied) We established two novel glioma subclones those showed different invasive and angiogenic phenotypes. J3T-1 demonstrates robust angiogenesis and perivascular invasion. J3T-2 demonstrates diffuse invasion along white matter tracts. We used microarrays to show the difference of gene expression that contribute to the difference of phenotype.

Organism:

Canis lupus familiaris

Type:

Expression profiling by array

Platform:

GPL3738

2 Samples

Download data: CEL