Similar studies for GEO DataSets (Select 787) - GEO DataSets

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Items: 4

Select item 7871.

Presenilin 1 and 2 conditional double knockout effect on brain cerebral cortex

Expression profiling of brain cerebral cortex from presenilin (PS) 1 and 2 conditional double knockout (cDKO) mutant at 6 months of age. PS inactivation is restricted to the forebrain. PS1 and PS2 mutations cause familial Alzheimer's disease. Inflammatory markers upregulated in PS cDKO.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL81
Series:: GSE1375
2 Samples

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DataSet

Accession:: GDS787

ID:: 787

Select item 2000013752.

PS cDKO / Control, 6 months

(Submitter supplied) Gene expression profile of presenilin conditional double knockout cerebral cortex, comparing to control. Age of mice: 6 months Keywords = presenilin knockout Keywords: parallel sample

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS787
Platform:: GPL81
2 Samples

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Series

Accession:: GSE1375

ID:: 200001375

Select item 2000007723.

Abeta-activated Array Experiment

(Submitter supplied) This series represents the samples used to generate the associated gene listing. The samples contained belong to two Platform accessions GPL561 and GPL562. There is a slight redundancy in the gene list due to multiple strong hits for a given gene. Clone selection was based on a fold >= 1.2 with a p-value <= 0.1 in at least 2 probe samples. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL562 GPL561
143 Samples

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Series

Accession:: GSE772

ID:: 200000772

Select item 2000636174.

Gene expression profiling of the AD11 anti-NGF transgenic mouse model of neurodegeneration at 1, 3, 6, 15 months of age

(Submitter supplied) We characterized the gene expression profile of brain regions at different stages of the Alzheimer’s like neurodegeneration in the anti-NGF AD11 trangenic mouse model. Total RNA was extracted from hippocampus, cortex and basal forebrain of postnatal day 30 (P30, 1 month), P90 (3 months), P180 (6 months) and at 15 months of age. Expression profiles were studied by Agilent microarray analysis, followed by qRT-PCR validation of significant candidates. more...