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Full record GDS4955

Prostate cancer cell line response to overexpression of Twist1 and Twist1 mutants

Analysis of Myc-Cap prostate cancer (PC) cells overexpressing Twist1 and mutants F191G, AQA, and DQD. Twist1, a basic helix-loop-helix transcription factor, is a master regulator of EMT that promotes cancer metastasis. Results provide insight into molecular basis of Twist1-induced PC metastasis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 5 genotype/variation sets
Platform:
GPL6246
Series:
GSE50002
15 Samples
Download data: CEL

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