Bruton's tyrosine kinase mutant models of X-linked agammaglobulinemia - - GEO DataSets

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Bruton's tyrosine kinase mutant models of X-linked agammaglobulinemia

Analysis of splenic B cells from mutants with a knockout of Bruton's tyrosine kinase (Btk) or a R28C missense mutation in Btk. Btk mutations cause a block in B cell differentiation and lead to X-linked agammaglobulinemia (XLA). Results provide insight into the pathogenesis of XLA.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 genotype/variation sets

Platform:: GPL81
Series:: GSE2826
6 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1346

ID:: 1346

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