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Full record GDS2160

CH1 domain deletions in p300 and CBP effect on hypoxic fibroblasts

Analysis of hypoxic fibroblasts bearing deletions in the CH1 domains of 1 allele of p300 and 2 alleles of CBP. CH1 domains interact with the C-TAD domain of hypoxia-inducible transcription factors HIF-1a and -2a. Results provide insight into the role of CH1 domains in the hypoxia response.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 stress sets
Platform:
GPL339
Series:
GSE3195
4 Samples
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