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Full record GDS3491

Aire ectopic expression effect on pancreatic islet beta cells

Analysis of pancreatic islet beta cells ectopically expressing Aire. Aire promotes T cell tolerance by inducing the expression of genes encoding peripheral tissue antigens in medullary epithelial cells of the thymus. Results provide insight into the specificity of Aire's effect on transcription.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 4 genotype/variation sets
Platform:
GPL1261
Series:
GSE12073
12 Samples
Download data: CEL

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