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Full record GDS3495

Progerin expression in a hTERT-immortalized skin fibroblast cell line: time course

Analysis of skin fibroblasts induced to express GFP-progerin for up to 10 days. Progerin is a mutant form of lamin A and the causal agent of premature-ageing disease Hutchinson-Gilford Progeria Syndrome (HGPS). Results provide insight into molecular mechanisms underlying this pathological effect.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol, 3 time sets
Platform:
GPL2895
Series:
GSE10123
12 Samples
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