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Full record GDS4333

Interleukin-2 null effect on the regulatory T cell-deficient scurfy model of autoimmune disease: CD4+ T-cells

Analysis of CD4+ T cells purified from pooled peripheral lymph nodes of scurfy (Sf) mice deficient in interleukin-2. Sf.Il2-/- mice develop liver inflammation, but not inflammation of skin and lung, seen in Sf mice. Results provide insight into role of IL2 in multiorgan inflammation in Sf mice.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE23398
7 Samples
Download data: CEL

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