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Full record GDS4338

Cyclooxygenase-2 overexpression or deletion effect on the K-ras/Pten pancreatic ductal adenocarcinoma murine model

Analysis of PDACs from mutants with pancreatic-specific Pten loss (Pten +/-) and K-ras activation (K-rasG12D) and either COX-2 over-expression (Cox-2 COE) or knockout (Cox-2 KO) under regulation of the Pdx-1 promoter. Results provide insight into the role of COX-2 in pancreatic cancer development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE38988
8 Samples
Download data: CEL

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