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Full record GDS4509

Progeroid and revertant phenotypes in primary dermal fibroblast cell line GM00038

Analysis of fibroblasts expressing progerin (the mutant lamin A associated with progeria) or elevated levels of wildtype prelamin A. Cells subsequently reverted towards normal by farnesyltransferase inhibitor (FTI) or ZMPSTE24 treatment. Results identify potential effector of lamin A dysfunction.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 6 protocol sets
Platform:
GPL570
Series:
GSE40404
7 Samples
Download data: CEL

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