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Items: 3

1.

RNA-Seq and Ribo-Seq analyses of the study "tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa"

(Submitter supplied) The success of bacterial pathogens depends on the coordinated expression of virulence determinants. Regulatory circuits that drive pathogenesis are complex, multilayered, and incompletely understood. Here, we reveal that alterations in tRNA modifications define pathogenic phenotypes in the opportunistic pathogen Pseudomonas aeruginosa. We demonstrate that the enzymatic activity of GidA leads to the introduction of a carboxymethylaminomethyl modification in selected tRNAs. more...
Organism:
Pseudomonas aeruginosa UCBPP-PA14
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL27892
12 Samples
Download data: BED
Series
Accession:
GSE233297
ID:
200233297
2.

tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Pseudomonas aeruginosa; Pseudomonas aeruginosa UCBPP-PA14
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL27892 GPL18287
18 Samples
Download data: BED
Series
Accession:
GSE149306
ID:
200149306
3.

RNA-Seq analysis for the study "tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa"

(Submitter supplied) The success of bacterial pathogens depends on the coordinated expression of virulence determinants. Regulatory circuits that drive pathogenesis are complex, multilayered, and incompletely understood. Here, we reveal that alterations in tRNA modifications define pathogenic phenotypes in the opportunistic pathogen Pseudomonas aeruginosa. We demonstrate that the enzymatic activity of GidA leads to the introduction of a carboxymethylaminomethyl modification in selected tRNAs. more...
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18287
6 Samples
Download data: XLSX
Series
Accession:
GSE149304
ID:
200149304
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