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Links from PMC

Items: 9

1.

An epigenetic gene signature underlies phenotype switching in early stage melanomas.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Protein profiling by protein array; Expression profiling by array
Platforms:
GPL32054 GPL32055 GPL18573
300 Samples
Download data: BW, RCC, SF
Series
Accession:
GSE198432
ID:
200198432
2.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [Nanostring_sample3]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL32055
82 Samples
Download data: RCC
Series
Accession:
GSE198431
ID:
200198431
3.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [nanotstring_sample2]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL32055
124 Samples
Download data: RCC
Series
Accession:
GSE198430
ID:
200198430
4.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [Nanostring_sample1]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL32055
35 Samples
Download data: RCC
Series
Accession:
GSE198429
ID:
200198429
5.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [RPPA]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.
Organism:
Homo sapiens
Type:
Protein profiling by protein array
Platform:
GPL32054
15 Samples
Download data
Series
Accession:
GSE198428
ID:
200198428
6.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [YUCHIME]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: SF
Series
Accession:
GSE198427
ID:
200198427
7.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [SKMel147]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: SF
Series
Accession:
GSE198426
ID:
200198426
8.

Next Generation Sequencing of Primary Melanocytes, Epgn1, and Epgn3 Melanoma Cell lines [RNA-seq]

(Submitter supplied) Purpose: The goals of this study are to identify differentially expressed genes between two groups of melanoma cell lines (Epgn1 and Epgn3) as compared to control melanocytes. Methods: Melanoma cell line profiles of control melanocytes and primary human cell lines were generated by deep sequencing 75bp paired end reads, in triplicate, using Illumina NextSeq500. Reads were aligned and counts called using STAR. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
24 Samples
Download data: CSV
Series
Accession:
GSE198425
ID:
200198425
9.

An epigenetic gene signature underlies phenotype switching in early stage melanomas [ChIP-seq]

(Submitter supplied) A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups. H3K27Ac ChipSeq profiles of primary human melanoma cell lines (n=4) as well as corresponding input samples were generated by deep sequencing using Illumina NextSeq500. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
8 Samples
Download data: BW
Series
Accession:
GSE197235
ID:
200197235
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