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CpG island hypermethylation in human astrocytomas

(Submitter supplied) Astrocytomas are common and lethal human brain tumors. Here, we have analyzed the methylation status of over 28,000 CpG islands and 18,000 promoters in normal human brain and in astrocytomas of various grades using the methylated-CpG island recovery assay (MIRA). We identified six to seven thousand methylated CpG islands in normal human brain. ~5% of the promoter-associated CpG islands in normal brain are methylated. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL9771
36 Samples
Download data: GFF, TXT
Series
Accession:
GSE19391
ID:
200019391

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