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A gene expression signature predicting the recurrence of tamoxifen-treated primary breast cancer.

(Submitter supplied) A 36-gene classifier was constructed through expression profiling of 132 tumors from tamoxifen-treated patients using 70-mer oligonucleotide microarrays. The robustness of the signature was demonstrated using expression data from 83 independent tumors. The 36-gene signature was (i) more efficient to predict disease-free survival than the traditional histo-pathological prognostic factors, (ii) as effective as the Nottingham Prognostic Index or the "Adjuvant!" software, and (iii) the only independent prognostic factor. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5049
155 Samples
Download data: GPR, TXT
Series
Accession:
GSE9893
ID:
200009893

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