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Items: 2

1.

Non-steroidal Anti-inflammatory Drugs Decrease E2F1 Expression and Inhibit Cell Growth in Ovarian Cancer Cells

(Submitter supplied) Epidemiological studies have shown that the regular use of non-steroidal anti-inflammatory (NSAIDs) drugs is associated with a reduced risk of various cancers. In addition, in vitro and experiments in mouse models have demonstrated that NSAIDs decrease tumor initiation and/or progression of several cancers. However, there are limited preclinical studies investigating the effects of NSAIDs in ovarian cancer. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5353
Platform:
GPL6104
9 Samples
Download data: TXT
Series
Accession:
GSE45052
ID:
200045052
2.
Full record GDS5353

Non-steroidal anti-inflammatory drug treatment effect on serous ovarian adenocarcinoma cell lines

Analysis of ovarian adenocarcinoma cell lines HEY, OVCAR5 and UCI-101 treated 24h with NSAIDs diclofenac or indomethacin (300mM). NSAID drugs associated with a reduced risk of various cancers. Results provide insight into molecular pathways mediating effects of NSAID treatment in ovarian cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 agent, 3 cell line sets
Platform:
GPL6104
Series:
GSE45052
9 Samples
Download data

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