GEO DataSet Links for PMC (Select 3774565) - GEO DataSets

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Items: 2

Select item 2000153491.

Skeletal muscle gene expression after myostatin knockout in mature mice

(Submitter supplied) RNA from 5 mice with postdevelopmental knockout of myostatin and 5 mice with normal myostatin expression was analyzed with comprehensive oligonucleotide microarrays. Myostatin depletion affected the expression of several hundred genes at nominal P < 0.01, but fewer than a hundred effects were statistically significant according to a more stringent criterion (false discovery rate < 5%). Most of the effects were less than 1.5-fold in magnitude. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3637
Platform:: GPL1261
10 Samples

Download data: CEL

Series

Accession:: GSE15349

ID:: 200015349

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 36372.

Myostatin depletion effect on mature skeletal muscle

Analysis of mature skeletal muscle depleted for the TBFb protein myostatin (MSTN). MSTN inhibits muscle differentiation and growth. MSTN deficiency during development results in muscle hypertrophy. Results provide insight into the effect of reducing MSTN activity after normal muscle development.