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Items: 2

1.

Neoadjuvant anastrozole alone or with gefitinib in early breast cancer

(Submitter supplied) Trial 223 was a placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer. We used patients from arm B and C: anastrozole 1mg/d for the duration of the 16 week period plus placebo 1 tablet/d orally for 2 weeks. Patients in arm B were followed by gefitinib 250mg/d orally for 14 weeks whereas patients in arm C continued with placebo for 14 weeks.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
96 Samples
Download data: CEL
Series
Accession:
GSE48906
ID:
200048906
2.

The NEWEST trial

(Submitter supplied) The NEWEST (Neoadjuvant Endocrine Therapy for Women with Estrogen-Sensitive Tumours) trial compared the clinical and biological activity of fulvestrant 500 mg vs 250 mg in the neoadjuvant setting. In this multi-centre phase II study, post-menopausal women with operable, locally advanced (T2, 3, 4b; N0-3; M0) ER-positive breast tumours were randomised to receive neoadjuvant treatment with either dose of fulvestrant for 16 weeks before surgery. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
42 Samples
Download data: CEL
Series
Accession:
GSE48905
ID:
200048905

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