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Items: 2

1.

Silica nanoparticles effects on gene expression of A549 cells

(Submitter supplied) Expansion of nanotechnology will bring many potential benefits as adversely effects on human health. Protection of the human respiratory system from exposure of volatile nanoparticles has become an emerging health concern. The understanding of the biological processes involved in the development and maintenance of a variety of pathologies is improved by genome-wide approaches. Technical feasibility of this type of experiment has perfected in recent years, but data analysis remains challenging. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5206
Platform:
GPL6480
18 Samples
Download data: TXT
Series
Accession:
GSE53700
ID:
200053700
2.
Full record GDS5206

Silica nanoparticle effect on lung adenocarcinoma epithelial A549 cells

Analysis of A549 cells treated with SiO2 NPs (diameters of 9nm and 18nm) and examined after 3hr and 22hr recovery times. Coated nanomaterials (e.g., SiO2 NPs) agglomerate less and are, thus, more easily inhalable. Results provide molecular insight into molecular basis of nanotoxicological effects.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 2 time sets
Platform:
GPL6480
Series:
GSE53700
18 Samples
Download data: TXT

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