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Items: 3

1.

microRNA-27a contributes to rhabdomyosarcoma cell proliferation through suppression of RARA and RXRA

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. Background: Rhabdomyosarcomas (RMS) are rare but very aggressive tumors of childhood that arise as a consequence of regulatory distruption of the growth and differentiation pathways of myogenic precursor cells. Based on morphology, two major RMS subtypes can be identified: embryonal RMS (ERMS) and alveolar (ARMS). So, it is essential to unravel the molecular mechanisms involved in cancer pathogenesis and in disease progression. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL17835 GPL6480
22 Samples
Download data: CSV, TXT
Series
Accession:
GSE52679
ID:
200052679
2.

Gene expression profiling of miR27a over-expressing RH36 cell lines.

(Submitter supplied) In order to identify direct or indirect miR-27a modulated genes, RH36 cells transfected with miR-27a precursors (pre-miR-27a or pre-control), analyzed 48h post-transfection, were used to perform microarray analysis.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
6 Samples
Download data: TXT
Series
Accession:
GSE52678
ID:
200052678
3.

miRNA expression profiling in rhabdomyosarcoma cell lines

(Submitter supplied) Rhabdomyosarcomas (RMS) are rare but very aggressive tumours of childhood that arise as a consequence of regulatory disruption of the growth and differentiation pathways of myogenic precursor cells. Based on morphology, two major RMS subtypes can be identified: embryonal RMS (ERMS) and alveolar (ARMS). To better understand the global function of miRNA in RMS, we analyzed the expression profile of 8 different RMS cell lines (3 PAX3/FOXO1 positive and 5 PAX3/FOXO1 negative RMS) using the mirVana miRNA Probe Set V1 (Ambion). more...
Organism:
Homo sapiens; Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL17835
16 Samples
Download data: CSV
Series
Accession:
GSE52677
ID:
200052677
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