GEO DataSet Links for PMC (Select 5435862) - GEO DataSets

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Items: 2

Select item 2000925651.

High depth sequencing of BrU-labeled nascent RNA.

(Submitter supplied) BrU incorporation into nascent RNA followed by immunoprecipitation with a BrU specific antibody. The nascent RNA was subsequently eluted with BrU competition.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
4 Samples

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Accession:: GSE92565

ID:: 200092565

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000568622.

Genome-wide quantification of microRNA processing efficiency from RNA-seq data

(Submitter supplied) Microprocessor is responsible for conversion of pri-miRNA transcripts into pre-miRNA hairpins in miRNA biogenesis. The in vivo properties of this process remain enigmatic. Here, we present the first study of in vivo transcriptome-wide pri-miRNA processing using next-generation sequencing of chromatin-associated pri-miRNAs. We identify a distinctive Microprocessor signature in the transcriptome profile, from which efficiency of the endogenous processing event can be accurately quantified. more...