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Items: 5

1.

Rif1 Promotes a Repressive Chromatin State to Safeguard Against Endogenous Retrovirus Activation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platform:
GPL19057
22 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE98256
ID:
200098256
2.

Rif1 Promotes a Repressive Chromatin State to Safeguard Against Endogenous Retrovirus Activation [RNA-seq]

(Submitter supplied) Transposable elements, including endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome. They are transcriptionally silenced during early development to protect genome integrity and aberrant transcription. However, the mechanisms that control their repression are not fully understood. To systematically study ERV repression, we carried out an RNAi screen in mouse embryonic stem cells (ESCs) and identified a list of novel regulators. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
4 Samples
Download data: TXT
Series
Accession:
GSE98255
ID:
200098255
3.

Rif1 Promotes a Repressive Chromatin State to Safeguard Against Endogenous Retrovirus Activation [MeDIP-seq]

(Submitter supplied) Transposable elements, including endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome. They are transcriptionally silenced during early development to protect genome integrity and aberrant transcription. However, the mechanisms that control their repression are not fully understood. To systematically study ERV repression, we carried out an RNAi screen in mouse embryonic stem cells (ESCs) and identified a list of novel regulators. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: BEDGRAPH
Series
Accession:
GSE98254
ID:
200098254
4.

Rif1 Promotes a Repressive Chromatin State to Safeguard Against Endogenous Retrovirus Activation [ChIP-seq]

(Submitter supplied) Transposable elements, including endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome. They are transcriptionally silenced during early development to protect genome integrity and aberrant transcription. However, the mechanisms that control their repression are not fully understood. To systematically study ERV repression, we carried out an RNAi screen in mouse embryonic stem cells (ESCs) and identified a list of novel regulators. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
14 Samples
Download data: BEDGRAPH
Series
Accession:
GSE98253
ID:
200098253
5.

Rif1 Promotes a Repressive Chromatin State to Safeguard Against Endogenous Retrovirus Activation [ATAC-seq]

(Submitter supplied) Transposable elements, including endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome. They are transcriptionally silenced during early development to protect genome integrity and aberrant transcription. However, the mechanisms that control their repression are not fully understood. To systematically study ERV repression, we carried out an RNAi screen in mouse embryonic stem cells (ESCs) and identified a list of novel regulators. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: BEDGRAPH
Series
Accession:
GSE98252
ID:
200098252
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