GEO DataSet Links for PMC (Select 5768915) - GEO DataSets

Select item 2001062001.

RNA differencial expression data between scrambled siRNA-treated mice and HN1L siRNA-treated mice tumor samples

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL19117 GPL570
20 Samples

Download data: CEL

Series

Accession:: GSE106200

ID:: 200106200

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001061992.

MicroRNA differencial expression data between scrambled siRNA-treated mice and HN1L siRNA-treated mice tumor samples

(Submitter supplied) (HN1L) is a targetable breast cancer stem cell (BCSC) gene that is altered in 25% of whole breast cancer and significantly correlated with shorter overall or relapse-free survival in triple negative breast cancer (TNBC) patients. HN1L silencing reduced the population of BCSCs, inhibited tumor initiation, re-sensitized chemo-resistant tumors to docetaxel, and hindered cancer progression in multiple TNBC cell line derived xenografts. more...

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL19117
10 Samples

Download data: CEL, TXT

Series

Accession:: GSE106199

ID:: 200106199

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001061063.

mRNA differencial expression data between scrambled siRNA-treated mice and HN1L siRNA-treated mice tumor samples

(Submitter supplied) (HN1L) is a targetable breast cancer stem cell (BCSC) gene that is altered in 25% of whole breast cancer and significantly correlated with shorter overall or relapse-free survival in triple negative breast cancer (TNBC) patients. HN1L silencing reduced the population of BCSCs, inhibited tumor initiation, re-sensitized chemo-resistant tumors to docetaxel, and hindered cancer progression in multiple TNBC cell line derived xenografts. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
10 Samples

Download data: CEL, TXT

Series

Accession:: GSE106106

ID:: 200106106

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001054464.

ChIP-seq analysis of HN1L protein in SUM159 triple-negative breast cancer cells

(Submitter supplied) Purpose: The goal of this study is to identify the role of HN1L protein as a transcription factor or co-factor in regulating TNBC cells. Methods: Due to the unavailability of a ChIP-grade HN1L antibody, we overexpressed FLAG-tagged HN1L in SUM159 cells and performed ChIP using anti-FLAG antibodies. ChIP DNA was prepared into libraries and sequenced by the Epigenomics Core of Weill Cornell Medical College using SR50 lane. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
2 Samples

Download data: TXT

Series

Accession:: GSE105446

ID:: 200105446

PubMed Full text in PMC Similar studies SRA Run Selector

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