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Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice

(Submitter supplied) Diminished colonic health is associated with various age-related pathologies. In this study, we applied an integrative approach to reveal potential interactions between determinants of colonic health in aging C57BL/6J mice. Analysis of gut microbiota composition revealed an enrichment of various potential pathobionts, including Desulfovibrio spp., and a decline of the health-promoting Akkermansia spp. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11533
26 Samples
Download data: CEL
Series
Accession:
GSE113257
ID:
200113257

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