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Gene expression profile of conjunctival epithelial cell lines

(Submitter supplied) Human conjunctival cell lines are useful tools for modeling ocular surface disease and evaluation of ocular drugs. Here we demonstrate that the IOBA-NHC and the ChWK conjunctival epithelial cell lines show, using an unbiased gene microarray approach, unique gene expression signatures that differ from primary conjunctival epithelial cells (PCEC) and conjunctival tissue. Globally, the expression profile obtained with the Affymetrix U133A chip (>22000 genes) from PCEC was clustered more closely to conjunctival tissue than either of the 2 cell lines. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
16 Samples
Download data: CEL
Series
Accession:
GSE8633
ID:
200008633

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