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Items: 3

1.

Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL6801 GPL10558
31 Samples
Download data: CEL, CHP
Series
Accession:
GSE99003
ID:
200099003
2.

Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome [Affymetrix]

(Submitter supplied) Combination of CDK4/6 inhibitors and endocrine therapy has been shown to improve clinical outcome in advanced estrogen receptor-positive breast cancer. However, not all patients will benefit and relapse is inevitable making the identification of new therapeutic strategies/biomarkers of particular importance.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; SNP genotyping by SNP array
Platform:
GPL6801
8 Samples
Download data: CEL, CHP
Series
Accession:
GSE99002
ID:
200099002
3.

Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome [Illumina]

(Submitter supplied) Combination of CDK4/6 inhibitors and endocrine therapy has been shown to improve clinical outcome in advanced estrogen receptor-positive breast cancer. However, not all patients will benefit and relapse is inevitable making the identification of new therapeutic strategies/biomarkers of particular importance.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
23 Samples
Download data: TXT
Series
Accession:
GSE98987
ID:
200098987
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