GEO DataSet Links for PMC (Select 8458072) - GEO DataSets

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Items: 3

Select item 2001614451.

The Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homeostasis and repair

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL23479
8 Samples

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Accession:: GSE161445

ID:: 200161445

PubMed Full text in PMC Similar studies

Select item 2001614432.

The Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homeostasis and repair [SMART-SeqII]

(Submitter supplied) Objective: Tissue stem cells are central regulators of organ homeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferating isthmus stem cells in the stomach corpus. Design: We uncovered the specific expression of Iqgap3 in proliferating isthmus stem cells through immunofluorescence and in situ hybridization. We performed lineage tracing and transcriptomic analysis of Iqgap3+ isthmus stem cells with the Iqgap3-2A-tdTomato mouse model. more...