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Genome-wide analysis of Ischaemia-Reperfusion damage in human bowel

(Submitter supplied) Comprehensive understanding of the transcriptional foundations of human intestinal ischemia-reperfusion (IR) injury is imperative to find therapeutic targets and improve patient outcome. Here we analysed transcriptomes of the IR-injured human intestine, and showed that over 1,800 genes were significantly differentially expressed, predominantly during reperfusion. Intriguingly, protein processing in endoplasmic reticulum (ER) was one of the most perturbed pathways, which was supported by ontology analysis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
28 Samples
Download data: TXT
Series
Accession:
GSE37013
ID:
200037013

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