GEO DataSets

(Submitter supplied) Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres were discovered on non-repetitive DNA. To test whether centromeres have a special chromatin structure we have analysed the architecture of a neocentromere. more...

Organism:

Homo sapiens; Cricetulus griseus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL31911

4 Samples

Download data: BEDGRAPH

(Submitter supplied) Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres were discovered on non-repetitive DNA. To test whether centromeres have a special chromatin structure we have analysed the architecture of a neocentromere. more...

Organism:

Cricetulus griseus; Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL31910

8 Samples

Download data: BW

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Cricetulus griseus; Homo sapiens

Type:

Genome binding/occupancy profiling by genome tiling array; Expression profiling by high throughput sequencing

4 related Platforms

68 Samples

Download data: TXT

(Submitter supplied) This study was designed to investigate the chromatin structure of human centromeres. Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres were discovered on non-repetitive DNA. more...

Organism:

Cricetulus griseus; Homo sapiens

Type:

Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL31868 GPL31869

39 Samples

Download data: TXT

(Submitter supplied) This study was designed to investigate the chromatin structure of human centromeres. Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres were discovered on non-repetitive DNA. more...

Organism:

Cricetulus griseus; Homo sapiens

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL31869

7 Samples

Download data: TXT

(Submitter supplied) This study was designed to investigate the chromatin structure of human centromeres. Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres were discovered on non-repetitive DNA. more...

Organism:

Cricetulus griseus; Homo sapiens

Type:

Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL31868 GPL31869

10 Samples

Download data: TXT