GEO DataSet Links for SRA (Select 27232407) - GEO DataSets

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Links from SRA

Items: 2

Select item 3071423321.

LNCaP_LIN37_DF_EtOH

Organism:: Homo sapiens

Source name:: LNCaP

Platform:: GPL16791
Series:: GSE228895 GSE228897

Download data: NARROWPEAK

Sample

Accession:: GSM7142332

ID:: 307142332

SRA Run Selector

Select item 2002288952.

Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor Through cMYC Repression and Recruitment of the DREAM Complex [ChIP-seq]

(Submitter supplied) The androgen receptor (AR) pathway regulates key cell survival programs in prostate epithelium. Targeting the AR has a remarkable therapeutic index and represents a near-universal driver and therapeutic vulnerability in metastatic prostate cancer. Though most approaches directed toward the AR focus on inhibiting AR signaling, laboratory and now clinical data have shown that high dose, supraphysiological androgen treatment (SPA), results in growth repression and improved out-comes in subsets of prostate cancer patients. more...