GEO DataSet Links for SRA (Select 36627787) - GEO DataSets

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Items: 2

Select item 3086945271.

CACO2shADAR1-2.Input

Organism:: Homo sapiens

Source name:: colorectum

Platform:: GPL18460
Series:: GSE284992

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Accession:: GSM8694527

ID:: 308694527

SRA Run Selector

Select item 2002849922.

Overview of distinct 8-Oxoguanine profiles of messenger RNA in normal and senescent cancer cells

(Submitter supplied) Background: Cellular senescence plays a key role in the development of cancer, but the underlying mechanisms are unknown.Recently, several recent studies have shown that RNA methylation is closely related to cancer cell aging. 8-Oxoguanine (o8G) is an important and widely distributed methylation modification whose role in cancer cell senescence is far from elucidated. Methods: In this study, senescent cancer cell models (CaCO2 cells) were constructed by knocking down the ADAR1 gene. more...