GEO DataSet Links for SRA (Select 5979299) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from SRA

Items: 2

Select item 3032900151.

dproQ_LB_R3

Organism:: Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344

Source name:: S. Typhimurium_in-vitro conditions

Platform:: GPL20056
Series:: GSE117255 GSE117256

Download data

Sample

Accession:: GSM3290015

ID:: 303290015

SRA Run Selector

Select item 2001172552.

Role of ProQ in Salmonella virulence - in vitro

(Submitter supplied) FinO-domain proteins such as ProQ of the model pathogen Salmonella enterica have emerged as a new class of major RNA-binding proteins in bacteria. ProQ has been shown to target hundreds of transcripts including mRNAs from many virulence regions but its role, if any, in bacterial pathogenesis has not been studied. Here, using a Dual RNA-seq approach to profile ProQ-dependent gene expression changes as Salmonella infects human cells, we reveal dysregulation of bacterial motility, chemotaxis and virulence genes which is accompanied by altered mitogen-activated protein kinase signaling in the host. more...