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Items: 2

1.

FL 5

Organism:
Mus musculus
Source name:
Liver
Platform:
GPL17021
Series:
GSE141077
Download data
Sample
Accession:
GSM4194556
ID:
304194556
2.

The hepatic transcriptome of liver-specific insulin receptor knockout (LIRKO) mouse offspring

(Submitter supplied) At 2 months of age, liver-specific insulin receptor knockout (LIRKO) mice present hyperglycemia and hyperinsulinemia. Furthermore, LIRKO mice have increased levels of hepatic cholesterol. Indeed, many changes seen in cholesterol metabolism in LIRKO mice are also observed in humans with metabolic syndrome. For example, both show decreased levels of HDL and increased secretion of apoB and VLDL. These findings make the LIRKO mouse a unique non-dietary model of insulin resistant, hyperglycemia, dyslipidemia and atherosclerosis that resembles several clinical features of the human metabolic syndrome. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
10 Samples
Download data: CSV
Series
Accession:
GSE141077
ID:
200141077

Supplemental Content

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