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Items: 1 to 20 of 329

1.

Designing of Lactococcus lactis platform for isobutanol production using multiple rounds of adaptive laboratory evolution

(Submitter supplied) This work was primarily focused on removing the main bottleneck for isobutanol production which is the toxicity of isobutanol towards its host and the major reason for its low-level production. Recently, there have been many reports where people have tried various strategies including continuous in-situ product removal from the bioreactor which led to a significant increase in the final product titers. more...
Organism:
Lactococcus cremoris
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24381
4 Samples
Download data: TXT
Series
Accession:
GSE107996
ID:
200107996
2.

L. lactis cultures: control vs acetaldehyde-induced

(Submitter supplied) Transcriptome analysis of Lactococcus lactis cultures comparing control non-induced and induced with acetaldehyde
Organism:
Lactococcus cremoris; Lactococcus lactis
Type:
Expression profiling by array
Platform:
GPL28321
6 Samples
Download data: GPR, XLSX
Series
Accession:
GSE147696
ID:
200147696
3.

L. lactis cultures: control vs diacetyl-induced

(Submitter supplied) Transcriptome analysis of Lactococcus lactis cultures comparing control non-induced and induced with diacetyl
Organism:
Lactococcus lactis; Lactococcus cremoris
Type:
Expression profiling by array
Platform:
GPL28321
6 Samples
Download data: GPR, XLSX
Series
Accession:
GSE147695
ID:
200147695
4.

The 3’UTR of ArgR regulates the arc operon

(Submitter supplied) ArgR and the sRNA from its 3’UTR, ArgX, both regulate the arc operon by influencing transcription and RNA stability/translation respectively
Organism:
Lactococcus cremoris
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24073
16 Samples
Download data: GFF, RPKM, TXT
Series
Accession:
GSE104515
ID:
200104515
5.

Target identification of the cold stress induced sRNA CisR in Lactococcus lactis

(Submitter supplied) Target identification of the cold stress induced sRNA CisR in Lactococcus lactis by CisR overexpression and MAPS technology
Organism:
Lactococcus cremoris
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24073
8 Samples
Download data: GFF, RPKM, TXT
Series
Accession:
GSE115974
ID:
200115974
6.

Transcriptome analysis of cellobiose-positive isolates of L. lactis MG1363

(Submitter supplied) Transcriptomes of L. lactis MG1363ΔcelBΔptcCΔ0963 containing either an IS905 or a gfp integrated into llmg_1239 (pseudo_39) were compared to that of MG1363 with a Pcel (llmg_0186)up-mutation An integration of IS905 into a gene coding for a transcriptional repressor led to activation of the repressed gene cluster coding for a plant sugar utilization pathway. The strain is further characterized using DNA MicroArrays.
Organism:
Lactococcus cremoris
Type:
Expression profiling by array
Platform:
GPL23996
16 Samples
Download data: TXT
Series
Accession:
GSE103707
ID:
200103707
7.

Transcriptomic analysis of Lactococcus lactis ssp. cremoris KW2 after ComX constitutive production

(Submitter supplied) Lactococcus lactis is one of the most important lactic acid bacterium used in the dairy industry. Activation of natural DNA transformation in this species would greatly improve the selection of novel strains with desired industrial traits. Here, we investigate the activation of natural transformation in L. lactis ssp. cremoris KW2, a strain of plant origin whose genome encodes the master competence regulator ComX and the complete set of essential late gene products required for natural transformation under its potential control. more...
Organism:
Lactococcus cremoris
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22400
2 Samples
Download data: XLSX
Series
Accession:
GSE86476
ID:
200086476
8.

Characterizition of a fast-growing Lactococcus lactis mutant on maltose

(Submitter supplied) Trade-offs often occurs during experimental evolution. For example, the degeneration of growth in glucose was found in a galactose adapted yeast. Here, we isolated one Lactococcus lactis mutant using experimental on maltose. The mutant grows normally on glucose, but faster than the wild-type on maltose and galactose. DNA microarray analysis and whole genome re-sequencing were applied to disclose the crucial points that determine the phenotype.
Organism:
Lactococcus cremoris subsp. cremoris MG1363
Type:
Expression profiling by array
Platform:
GPL13249
18 Samples
Download data: TXT
Series
Accession:
GSE56042
ID:
200056042
9.

Gene expression signature in Lactococcus lactis after ethanol, butanol or hexanol exposure

(Submitter supplied) Reference samples: Strain MG1363 was grown balanced in SAL medium supplemented with 1% glucose. Stressed samples: Strain MG1363 was exposed to either ethanol (55 mg/ml), butanol (10 ml/mg) or hexanol (2 mg/ml) in GSAL medium after balanced growth
Organism:
Lactococcus lactis; Lactococcus cremoris subsp. cremoris MG1363
Type:
Expression profiling by array
Platform:
GPL21561
18 Samples
Download data: TXT
Series
Accession:
GSE89508
ID:
200089508
10.

Gene expression signature after abrupt glucose starvation in Lactococcus lactis

(Submitter supplied) Stressed samples: Strain MG1363 was exposed to abrupt glucose depletion in SA medium after balanced growth. Reference sample: Strain MG1363 was grown balanced in SA medium containing 1% glucose
Organism:
Lactococcus lactis; Lactococcus cremoris subsp. cremoris MG1363
Type:
Expression profiling by array
Platform:
GPL21561
8 Samples
Download data: TXT
Series
Accession:
GSE78882
ID:
200078882
11.

L. lactis MG1363 transcriptome analysis of 4 evolved strains

(Submitter supplied) L. lactis MG1363 was evolved in 4 fermentors in glucose-containing chemically defined medium (CDMPC) for 309 generations at a dilution rate of 0.5h-1 Glycerol stocks made during the evolution experiment were revived in CDMPC and further characterized.
Organism:
Lactococcus cremoris; Lactococcus cremoris subsp. cremoris MG1363
Type:
Expression profiling by array
Platform:
GPL20601
4 Samples
Download data: TXT
Series
Accession:
GSE67657
ID:
200067657
12.

Lactococcus lactis MG1363 ∆guaA versus L. lactis MG1363 (wt)

(Submitter supplied) Gene expression in Lactococcus lactis MG1363 was compared to that of L. lactis MG1363 ∆guaA in rich GM17 medium.
Organism:
Lactococcus cremoris subsp. cremoris MG1363; Lactococcus lactis
Type:
Expression profiling by array
Platform:
GPL13944
1 Sample
Download data: TXT
Series
Accession:
GSE76764
ID:
200076764
13.

Transcriptome signatures for robustness of Lactococcus lactis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Lactococcus lactis; Lactococcus cremoris subsp. cremoris SK11; Lactococcus lactis subsp. lactis KF147; Lactococcus lactis subsp. lactis Il1403
Type:
Expression profiling by array
Platforms:
GPL20802 GPL20801 GPL20800
96 Samples
Download data
Series
Accession:
GSE72045
ID:
200072045
14.

Transcriptome signatures for robustness of Lactococcus lactis SK11

(Submitter supplied) Recently, we demonstrated that fermentation conditions strongly impact on subsequent survival of Lactococcus lactis strain MG1363 during heat and oxidative stress, two important parameters during spray drying. Moreover, employment of a transcriptome-phenotype matching approach revealed groups of genes associated with robustness towards heat and/or oxidative stress. To investigate if other strains have similar or distinct transcriptome signatures for robustness, we applied a similar transcriptome-robustness phenotype matching approach on the L. more...
Organism:
Lactococcus lactis; Lactococcus cremoris subsp. cremoris SK11
Type:
Expression profiling by array
Platform:
GPL20802
32 Samples
Download data: TXT
Series
Accession:
GSE72044
ID:
200072044
15.

Transcriptome profiling of Lactococcus lactis subsp. cremoris CECT 8666 in response to agmatine

(Submitter supplied) The goal was to determine the effect of agmatine on the trancriptional profile of L. lactis CECT 8666 strain. For that we compared the expression profile of L. lactis CECT 8666 cells grown in culture medium supplemented with 20 mM agmatine with the expression profile of L. lactis CECT 8666 cells grown in culture medium without agmatine.
Organism:
Lactococcus cremoris; Lactococcus cremoris subsp. cremoris GE214
Type:
Expression profiling by array
Platform:
GPL18969
5 Samples
Download data: GPR
Series
Accession:
GSE74808
ID:
200074808
16.

Characterization of a Lactococcus lactis high-temperature mutant with increased glycolytic flux

(Submitter supplied) Temperature is an important factor affecting biological organisms. We characterize a Lactococcus lactis (L. lactis) ssp. cremoris MG1363 mutant (CS3527) capable of growing better at a higher temperature than its parent. The transcriptomic analysis also revealed widespread down-regulation of genes encoding membrane transport proteins in the wild-type at 38°C. A fatty acid composition analysis revealed that the mutant has substantially more straight chained saturated and less cyclopropane fatty acids at 30°C and 38°C compared with the wild-type.
Organism:
Lactococcus lactis; Lactococcus cremoris subsp. cremoris MG1363
Type:
Expression profiling by array
Platform:
GPL13249
15 Samples
Download data: TXT
Series
Accession:
GSE27698
ID:
200027698
17.

Lactococcus lactis subsp. cremoris GE2-14 (GE2-14) vs Lactococcus lactis subsp. cremoris GE2-14 ΔaguR (GE2-14 ΔaguR)

(Submitter supplied) Trancriptional profiling of GE2-14 ΔaguR mutant strain in which the aguR gene of the agmatine deiminase cluster has been deleted. We compared the expression profiling of GE2-14 cells with the expression profiling of GE2-14 ΔaguR mutant cells. The goal was to determine the effect of the aguR deletion on the transcriptional profiling of GE2-14
Organism:
Lactococcus cremoris subsp. cremoris GE214
Type:
Expression profiling by array
Platform:
GPL18969
5 Samples
Download data: GPR
Series
Accession:
GSE59514
ID:
200059514
18.

Transcriptome signatures for robustness of Lactococcus lactis MG1363

(Submitter supplied) This study describes a transcriptome-phenotype matching approach in which the starter L. lactis MG1363 was fermented under a variety of conditions that differed in the levels of oxygen and/or salt, as well as the fermentation pH and temperature. Samples derived from these fermentations in the exponential phase of bacterial growth were analyzed by full-genome transcriptomics and the assessment of heat and oxidative stress phenotypes. more...
Organism:
Lactococcus cremoris subsp. cremoris MG1363; Lactococcus lactis
Type:
Expression profiling by array
Platform:
GPL18764
32 Samples
Download data: TXT
Series
Accession:
GSE58284
ID:
200058284
19.

Identification of tRNA sequences in Lactococcus lactis

(Submitter supplied) we report the identification and sequences of the tRNAome of industrially relevant microorganism Lactococcus lactis
Organism:
Lactococcus cremoris subsp. cremoris MG1363
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL18339
3 Samples
Download data: TXT
Series
Accession:
GSE55392
ID:
200055392
20.

Towards in vivo regulatory kinetics: PurR activation by PRPP during purine depletion in Lactococcus

(Submitter supplied) Short-term adaptation to changing environments relies on regulatory elements translating changing metabolite concentrations into a specifically optimized transcriptome. So far the focus of analyses has been divided between regulatory elements identified in vivo and kinetic studies of small molecules interacting with the regulatory elements in vitro. Here we describe how in vivo Regulatory Kinetics can describe a regulon through the effects of the metabolite controlling it, exemplified by temporal purine exhaustion in Lactococcus lactis. more...
Organism:
Lactococcus cremoris subsp. cremoris MG1363
Type:
Expression profiling by array
Platform:
GPL17895
15 Samples
Download data: TXT
Series
Accession:
GSE52135
ID:
200052135
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