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Items: 1 to 20 of 559

1.

in vitro and in vivo transcriptomics profile of Lactobacillus johnsonii MR1

(Submitter supplied) Lactobacillus johnsonii, a Gram-positive, gut bacterium is well studied for its several health-beneficial properties. This
Organism:
Lactobacillus johnsonii
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34689
16 Samples
Download data: TXT
Series
Accession:
GSE271801
ID:
200271801
2.

Vaginal Lactobacillus fatty acid response mechanisms reveal a metabolite-targeted strategy for bacterial vaginosis treatment

(Submitter supplied) Bacterial vaginosis (BV), a common syndrome characterized by Lactobacillus-deficient vaginal microbiota, is associated with adverse health outcomes. BV often recurs after standard antibiotic therapy in part because antibiotics promote microbiota dominance by Lactobacillus iners instead of Lactobacillus crispatus, which has more beneficial health associations. Strategies to promote L. crispatus and inhibit L. more...
Organism:
Lactobacillus crispatus; Lactobacillus gasseri; Lactobacillus jensenii
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL34635 GPL34636 GPL34634
36 Samples
Download data: FASTA, TSV, TXT
Series
Accession:
GSE270628
ID:
200270628
3.

Study of microbial species in extracellular vesicles of sclerosis multiple patients

(Submitter supplied) Extracellular vesicles (EVs) are released by most cell types and are implicated in several biological and pathological processes, including multiple sclerosis (MS). In this study we performed RNA sequencing to analyze the diversity of microorganisms by assignment of reads using different taxa profilers. To diminish the risk of false positive biases derived from sample handling, we performed a similar analysis on EVs derived from known cultured bacterial species, as well as artificially-generated samples. more...
Organism:
synthetic construct; Bifidobacterium animalis subsp. lactis; Lactobacillus acidophilus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
4 related Platforms
15 Samples
Download data: CSV
Series
Accession:
GSE255317
ID:
200255317
4.

Effect of growth temperature on gene expression of Lentilactobacillus kefiri and Lactobacillus kefiranofaciens co-culture

(Submitter supplied) We obtained L. kefiri (JCM5818) and L. kefiranofaciens (JCM6985) from the Japan Collection of Microorganisms (JCM). Bacteria were grown together at two different temperatures of 30C and 37C profiled for transcriptomics, metabolomics, and proteomics.
Organism:
Lentilactobacillus kefiri; Lactobacillus kefiranofaciens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33335
20 Samples
Download data: TXT
Series
Accession:
GSE229515
ID:
200229515
5.

Lactobacillus Firm5 in vivo and in vitro RNA sequencing

(Submitter supplied) We report the transcriptome of four strains of the Lactobacillus Firm5 phylotype obtained with in vivo and in vitro experiments under different nutrient conditions
Organism:
Lactobacillus melliventris; Lactobacillus kullabergensis; Lactobacillus helsingborgensis; Lactobacillus apis
Type:
Expression profiling by high throughput sequencing
6 related Platforms
49 Samples
Download data: TXT
Series
Accession:
GSE166724
ID:
200166724
6.

Method for absolute quantification of microbial communities by using both microarrays and competitive PCR

(Submitter supplied) We investigated an improved method that combines competitive PCR and microarray techniques. This approach allowed us to quantify specific bacterial groups mounted on DNA chips with accuracy close to that of real-time PCR, despite a measurement at the end point of PCR, and also to estimate the bacterial DNA content in sample DNA.
Organism:
Treponema denticola; Cereibacter sphaeroides; Streptococcus gordonii; Streptococcus agalactiae; Enterococcus faecalis; Bifidobacterium adolescentis; Homo sapiens; Prevotella intermedia; Prevotella nigrescens; Campylobacter rectus; Helicobacter pylori; Pseudomonas aeruginosa; Aggregatibacter actinomycetemcomitans; Phocaeicola vulgatus; Capnocytophaga gingivalis; Deinococcus radiodurans; Streptococcus mutans; Streptococcus intermedius; Cutibacterium acnes; Neisseria meningitidis; Porphyromonas gingivalis; Fusobacterium nucleatum; Clostridium beijerinckii; Lactobacillus gasseri; Tannerella forsythia; Bacteria; Acinetobacter baumannii; Escherichia coli; Staphylococcus aureus; Staphylococcus epidermidis; Bacillus cereus; Schaalia odontolytica; Fusobacterium nucleatum subsp. nucleatum
Type:
Other
Platform:
GPL25612
178 Samples
Download data: CSV
Series
Accession:
GSE125085
ID:
200125085
7.

Influence of manufacturing processes on cell surface properties of probiotic strain Lactobacillus rhamnosus Lcr35®

(Submitter supplied) Investigation of whole genome gene expression level changes in Lcr35® pharmaceutical formulations, compared to the native strain.
Organism:
Lactobacillus; Lacticaseibacillus rhamnosus
Type:
Expression profiling by array
Platform:
GPL18863
9 Samples
Download data: CALLS, PAIR
Series
Accession:
GSE58820
ID:
200058820
8.

Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress

(Submitter supplied) Exploring the mechanism of ethanol tolerance in Lactobacillus acetotolerans F28 and finding key genes which maybe participating in protecting cells from damage during ethanol stimulation.
Organism:
Lactobacillus acetotolerans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22840
12 Samples
Download data: TXT
Series
Accession:
GSE92732
ID:
200092732
9.

General Approach for Tetramer Based Identification of Autoantigen Reactive B Cells: Characterization of La and snRNP Reactive B Cells in Autoimmune BXD2 Mice

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Klebsiella pneumoniae; Porphyromonas gingivalis; Mycobacterium avium subsp. paratuberculosis; Mycobacterium tuberculosis; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human herpesvirus 4 strain B95-8; Human immunodeficiency virus 1; Human herpesvirus 4 type 1; Coxsackievirus B4 (strain E2); Proteus mirabilis; Streptococcus pyogenes; Mycobacterium gordonae; Trypanosoma cruzi; Caprine arthritis encephalitis virus; Human T-cell lymphotrophic virus type 1 (isolate MT-2); Human adenovirus 12; Human endogenous retrovirus K; Human Endogenous Retrovirus IDDMK1,2-22; Torque teno virus; Prochlorococcus marinus str. MIT 9202; Human rotavirus MP409; Paraburkholderia fungorum; Staphylococcus aureus A9635; Hepacivirus hominis; Helicobacter pylori; Yersinia enterocolitica; Chlamydia trachomatis; Mycobacterium tuberculosis variant bovis; Human alphaherpesvirus 2; Hepatitis C virus isolate HC-J6; Coxsackievirus B4; Coxsackievirus A20; Porphyromonas gingivalis W83; Mycobacterium avium subsp. paratuberculosis K-10; Escherichia coli; Shigella flexneri; Haemophilus influenzae; Staphylococcus aureus; Lactobacillus delbrueckii subsp. bulgaricus; Mycobacterium avium; Human betaherpesvirus 6; human gammaherpesvirus 4; Human T-cell leukemia virus type I; Coxsackievirus A9; Human herpesvirus 4 type 2; Chlamydia pneumoniae; Human poliovirus 3 strain Sabin; Betapolyomavirus macacae
Type:
Protein profiling by protein array
Platforms:
GPL19700 GPL19692 GPL19701
29 Samples
Download data: XLSX
Series
Accession:
GSE65290
ID:
200065290
10.

Autoimmune peptide antigen reactivity in BXD2 mice with spontaneous systemic autoimmune disease Pepperchip 2.0

(Submitter supplied) The aim of the array was to determine the BXD2 mouse sera IgG and IgM reactivity profile to linear peptide epitopes. Pooled sera from three 6-9 month old BXD2 mice was diluted at 1:200 for IgG specific analysis or 1:1000 for IgM specific analysis and incubated on a PEPperPRINT peptide microarray platform printed with peptide autoantigens
Organism:
Helicobacter pylori; Shigella flexneri; Yersinia enterocolitica; Human alphaherpesvirus 2; Hepatitis C virus isolate HC-J6; Human T-cell leukemia virus type I; Coxsackievirus A20; Torque teno virus; Prochlorococcus marinus str. MIT 9202; Paraburkholderia fungorum; Porphyromonas gingivalis W83; Mycobacterium avium subsp. paratuberculosis K-10; Staphylococcus aureus A9635; Haemophilus influenzae; Lactobacillus delbrueckii subsp. bulgaricus; Mycobacterium avium; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Coxsackievirus A9; Coxsackievirus B4 (strain E2); Betapolyomavirus macacae; Escherichia coli; Klebsiella pneumoniae; Proteus mirabilis; Porphyromonas gingivalis; Staphylococcus aureus; Mycobacterium avium subsp. paratuberculosis; Mycobacterium gordonae; Mus musculus; Human betaherpesvirus 6; Human immunodeficiency virus 1; Human herpesvirus 4 type 2; Human herpesvirus 4 type 1; Human endogenous retrovirus K; Chlamydia pneumoniae; Human poliovirus 3 strain Sabin; Chlamydia trachomatis; Streptococcus pyogenes; Mycobacterium tuberculosis variant bovis; Mycobacterium tuberculosis; Trypanosoma cruzi; Homo sapiens; Human herpesvirus 4 strain B95-8; Human T-cell lymphotrophic virus type 1 (isolate MT-2); Coxsackievirus B4; Human adenovirus 12; Human Endogenous Retrovirus IDDMK1,2-22; Human rotavirus MP409; Hepacivirus hominis
Type:
Protein profiling by protein array
Platform:
GPL19701
2 Samples
Download data: XLSX
Series
Accession:
GSE65278
ID:
200065278
11.

Autoimmune peptide antigen reactivity in normal B6 mice Pepperchip 2.0

(Submitter supplied) The aim of the array was to determine the B6 mouse sera IgG and IgM reactivity profile to linear peptide epitopes. Pooled sera from three 6-9 month old B6 mice was diluted at 1:200 for IgG specific analysis or 1:1000 for IgM specific analysis and incubated on a PEPperPRINT peptide microarray platform printed with peptide autoantigens
Organism:
Helicobacter pylori; Proteus mirabilis; Yersinia enterocolitica; Porphyromonas gingivalis; Mycobacterium gordonae; Human alphaherpesvirus 2; Hepatitis C virus isolate HC-J6; Human herpesvirus 4 type 1; Coxsackievirus A20; Torque teno virus; Paraburkholderia fungorum; Porphyromonas gingivalis W83; Mycobacterium avium subsp. paratuberculosis K-10; Escherichia coli; Klebsiella pneumoniae; Shigella flexneri; Staphylococcus aureus; Mycobacterium avium subsp. paratuberculosis; Mus musculus; Human immunodeficiency virus 1; Human herpesvirus 4 type 2; Chlamydia pneumoniae; Human poliovirus 3 strain Sabin; Haemophilus influenzae; Lactobacillus delbrueckii subsp. bulgaricus; Mycobacterium avium; Mycobacterium tuberculosis; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Human herpesvirus 4 strain B95-8; Human T-cell leukemia virus type I; Coxsackievirus A9; Prochlorococcus marinus str. MIT 9202; Coxsackievirus B4 (strain E2); Staphylococcus aureus A9635; Betapolyomavirus macacae; Chlamydia trachomatis; Streptococcus pyogenes; Mycobacterium tuberculosis variant bovis; Trypanosoma cruzi; Human betaherpesvirus 6; Human T-cell lymphotrophic virus type 1 (isolate MT-2); Coxsackievirus B4; Human adenovirus 12; Human endogenous retrovirus K; Human Endogenous Retrovirus IDDMK1,2-22; Human rotavirus MP409; Hepacivirus hominis
Type:
Protein profiling by protein array
Platform:
GPL19701
2 Samples
Download data: XLSX
Series
Accession:
GSE65277
ID:
200065277
12.

Genome-wide transcriptome analysis of the oxygen response of L. johnsonii reveals that NADH oxidase is a secondary H2O2 source.

(Submitter supplied) Oxidative stress due to endogenous hydrogen peroxide production by Lactobacillus species is a well-known issue in the food industry. In this study, the transcriptional response to oxygen of Lactobacillus johnsonii, one of the H2O2-producing strains used in the food industry, was analyzed. It was found that aerobic growth conditions led to a more than two-fold downregulation of 45 genes as compared to anaerobic growth, whereas 6 genes were more than twofold upregulated. more...
Organism:
Lactobacillus johnsonii
Type:
Expression profiling by array
Platform:
GPL18009
12 Samples
Download data: TXT
Series
Accession:
GSE52876
ID:
200052876
13.

Transcriptome-based characterization of the interactions between Saccharomyces cerevisiae and Lactobacillus delbrueckii subsp. bulgaricus in lactose-grown chemostat co-cultures

(Submitter supplied) The present study aims to explore chemostat-based transcriptome analysis of mixed cultures by investigating interactions between the yeast S. cerevisiae and the lactic acid bacterium Lb. bulgaricus . S. cerevisiae and Lb. bulgaricus are both frequently encountered in kefir, a fermented dairy product (25). In the context of this study, this binary culture serves as a model for the many traditional food and beverage fermentation processes in which yeasts and lactic acid bacteria occur together (19,26-30). more...
Organism:
Lactobacillus delbrueckii subsp. bulgaricus; Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL90
6 Samples
Download data: CEL
Series
Accession:
GSE45776
ID:
200045776
14.

Genome heterogeneity in Lactobacillus helveticus: Rethinking a “niche specialist”*

(Submitter supplied) Lactobacillus helveticus is a rod-shaped lactic acid bacterium that is widely used in the manufacture of fermented dairy foods and for production of bioactive peptides from milk proteins. Although L. helveticus is commonly associated with milk environments, phylogenetic studies show it is closely related to an intestinal species, Lactobacillus acidophilus, which has been shown to impart probiotic health benefits to humans. more...
Organism:
Lacticaseibacillus paracasei ATCC 334; Lactobacillus helveticus
Type:
Genome variation profiling by array
Platform:
GPL9271
42 Samples
Download data: CEL
Series
Accession:
GSE23660
ID:
200023660
15.

The gene expression characteristics involved in amino acids formation of Lactobacillus delbrueckii subsp. bulgaricus 2038

(Submitter supplied) Transcriptional profiling of Lactobacillus delbrueckii subsp. bulgaricus 2038 during the growth in casein proteins conditioned medium compared with the start control (cells treated in whey conditioned medium). Identifying the genes that are differentially expressed during the growth of Lb. bulgaricus 2038 in casein proteins condition provides a starting point for the investigation of metabolic mechanisms.
Organism:
Lactobacillus delbrueckii subsp. bulgaricus 2038
Type:
Expression profiling by array
Platform:
GPL17178
12 Samples
Download data: TXT
Series
Accession:
GSE47103
ID:
200047103
16.

Transcriptome-based characterization of the interactions between Saccharomyces cerevisiae and Lactobacillus delbrueckii subsp. bulgaricus in lactose-grown chemostat co-cultures

(Submitter supplied) The present study aims to explore chemostat-based transcriptome analysis of mixed cultures by investigating interactions between the yeast S. cerevisiae and the lactic acid bacterium L. bulgaricus . S. cerevisiae and L. bulgaricus are both frequently encountered in kefir, a fermented dairy product. In the context of this study, this binary culture serves as a model for the many traditional food and beverage fermentation processes in which yeasts and lactic acid bacteria occur together. more...
Organism:
Saccharomyces cerevisiae; Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365; Lactobacillus delbrueckii subsp. bulgaricus
Type:
Expression profiling by array
Platform:
GPL16855
4 Samples
Download data: TXT
Series
Accession:
GSE45623
ID:
200045623
17.

The human Gut Chip “HuGChip”, an explorative phylogenetic microarray for determining gut microbiome diversity at Family level

(Submitter supplied) A phylogenetic microarray targeting 66 families described in the human gut microbiota has been developped aud used to monitor the gut microbiota's structure and diversity. The microarray format provided by Agilent and used in this study is 8x15K. A study with a total of 4 chips was realized.
Organism:
uncultured bacterium; Lactobacillus acidophilus; human gut metagenome; Bacteroides fragilis; Escherichia coli; Blautia coccoides; [Clostridium] leptum
Type:
Expression profiling by array
Platform:
GPL16731
4 Samples
Download data: TXT
Series
Accession:
GSE44752
ID:
200044752
18.

Transcriptional analysis of prebiotic uptake and catabolism by Lactobacillus acidophilus NCFM

(Submitter supplied) The global transcriptome of the wild type Lactobacillus acidophilus NCFM strain (NCK56) was measured during exponential growth on 11 prebiotic carbohydrates and glucose to identify the specific gene cluster differentially upregulated in response to each carbohydrate.
Organism:
Lactobacillus acidophilus NCFM
Type:
Expression profiling by array
Platform:
GPL7374
12 Samples
Download data: TXT
Series
Accession:
GSE35968
ID:
200035968
19.

The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. (RNA-Seq)

(Submitter supplied) Understanding how the human gut microbiota and host are impacted by probiotic bacterial strains requires carefully controlled studies in humans, and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we characterized the fecal microbiomes and metatranscriptomes of adult female monozygotic twin pairs through repeated sampling 4 weeks prior to, 7 weeks during, and 4 weeks following consumption of a commercially-available fermented milk product (FMP) containing a consortium of Bifidobacterium animalis subsp. more...
Organism:
Ruminococcus; Lactobacillus; Lactobacillus delbrueckii subsp. bulgaricus; human gut metagenome; Bifidobacterium animalis subsp. lactis CNCM I-2494; Streptococcus thermophilus CNCM I-1630; Bacteroides; Collinsella; Streptococcus thermophilus; Clostridia; Parabacteroides; Lactococcus lactis subsp. lactis CNCM I-1631
Type:
Expression profiling by high throughput sequencing
4 related Platforms
73 Samples
Download data: TXT
Series
Accession:
GSE31670
ID:
200031670
20.

Lactobacillus plantarum IMDO 130201, a wheat sourdough isolate, adapts to growth in wheat sourdough simulation medium at different pH values through differential gene expression

(Submitter supplied) Sourdough is a very competitive and challenging environment for microorganisms. Usually, a stable microbiota composed of lactic acid bacteria (LAB) and yeasts comes to dominate this ecosystem. Although rich in carbohydrates, thus providing an ideal environment to grow, the low pH presents a particular challenge. The nature of the adaptation to this low pH was investigated for Lactobacillus plantarum IMDO 130201, an isolate from a laboratory wheat sourdough fermentation. more...
Organism:
Lentilactobacillus buchneri; Lactobacillus delbrueckii; Lactiplantibacillus pentosus; Lactobacillus gasseri; Limosilactobacillus reuteri; Lactobacillus amylovorus; Latilactobacillus curvatus; Lactobacillus johnsonii; Leuconostoc pseudomesenteroides; Enterococcus casseliflavus; Mammaliicoccus lentus; Limosilactobacillus panis; Companilactobacillus paralimentarius; Staphylococcus aureus; Enterococcus faecalis; Enterococcus hirae; Lactococcus lactis; Lacticaseibacillus casei; Lacticaseibacillus paracasei; Companilactobacillus farciminis; Limosilactobacillus fermentum; Fructilactobacillus sanfranciscensis; Bifidobacterium; Lacticaseibacillus rhamnosus; Enterococcus mundtii; Lentilactobacillus parabuchneri; Oenococcus oeni; Streptococcus thermophilus; Lactobacillus acidophilus; Weissella confusa; Lentilactobacillus hilgardii; Latilactobacillus sakei; Brevibacterium linens; Companilactobacillus mindensis; Leuconostoc mesenteroides; Pediococcus acidilactici; Pediococcus pentosaceus; Enterococcus faecium; Levilactobacillus brevis; Lactobacillus helveticus; Lactiplantibacillus plantarum; Companilactobacillus alimentarius; Fructilactobacillus fructivorans; Leuconostoc citreum; Limosilactobacillus pontis; Lactobacillus crispatus; Lactiplantibacillus paraplantarum; Limosilactobacillus frumenti; Furfurilactobacillus rossiae
Type:
Expression profiling by array
Platform:
GPL10874
10 Samples
Download data: TXT
Series
Accession:
GSE23945
ID:
200023945
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