GEO DataSets

(Submitter supplied) Methane-producing archaea are key organisms in the anaerobic carbon cycle. These organisms, also called methanogens, grow by converting substrate to methane gas in a process called methanogenesis. Previous research showed that reduction of the terminal electron acceptor is the rate-limiting step in methanogenesis by Methanosarcina acetivorans. In order to gain insight into how the cells sense and respond to availability of the terminal electron acceptor, we designed an experiment to deplete cells of the essential terminal oxidase enzyme, HdrED. more...

Organism:

Methanosarcina acetivorans C2A; Methanosarcina acetivorans

Type:

Expression profiling by array

Platform:

GPL34364

16 Samples

Download data: CALLS, PAIR, TXT

(Submitter supplied) Structure probing combined with next-generation sequencing (NGS) has provided novel insights into RNA structure-function relationships. To date such studies have focused largely on bacteria and eukaryotes, with little attention given to the third domain of life, archaea. Furthermore, functional RNAs have not been extensively studied in archaea, leaving open questions about RNA structure and function within this domain of life. more...

Organism:

Methanosarcina acetivorans C2A

Type:

Other

Platform:

GPL33336

12 Samples

Download data: TXT

(Submitter supplied) Methylated sulfur compounds, including dimethylsulfide (DMS), methylmercaptopropionic acid (MMPA) and methylsulfide (MeSH), are well-documented to play roles in global sulfur cycle and climate homeostasis, yet the molecular mechanisms of how they are metabolized by methanogens remain largely uncharacterized. Here, using high-throughtput sequencing of RNA (RNA-seq), we gained insight into how methanogens respond to methylated sulfur compounds at the transcriptional level.

Organism:

Methanosarcina acetivorans C2A

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19569

15 Samples

Download data: XLSX

(Submitter supplied) cat# A7240-00-01 Expr 4x72K arr Del-Microarrays for Expression Submitter states that the NDF file for this array was lost. Protocol: see website

Organism:

Methanosarcina acetivorans C2A

1 Series

16 Samples

Download data: TXT