GEO DataSets

(Submitter supplied) In this study we focused on understanding the effect of over expression of recombinant protective antigen (rPA) on the Bacillus anthracis metabolism and genes expression with the purpose of improving the production of this recombinant toxin in particular and recombinant proteins in general. To achieve this goal controlled growth of the B. anthracis ames strain transformed with pYS5 (PA producer) plasmid encoding protective antigen and the corresponding empty vector pSW4 (non-producer) were performed and protein production, bacterial growth characteristics and gene transcription pattern were analyzed. more...

Organism:

Bacillus anthracis str. Ames

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24488

18 Samples

Download data: TXT

(Submitter supplied) One of the cornerstones of an effective biodefense strategy is the ability to detect infectious agents with a high degree of sensitivity and specificity in the context of a complex sample background. The nature of the B. anthracis genome, however, renders specific detection difficult, due to close homology with B. cereus and B. thuringiensis. We therefore elected to determine the efficacy of next-generation sequencing analysis and microarrays for detection of B. more...

Organism:

synthetic construct; Bacillus anthracis str. Ames

Type:

Other

Platform:

GPL17345

24 Samples

Download data: PAIR

(Submitter supplied) Comparative Genomic Hybridization. Analysis of genomic content of closely related Bacillus species. Refer to individual records for strain information. Refer to platform and individual sample records for experimental protocols. Keywords: other

Organism:

Bacillus cereus; Bacillus anthracis; Bacillus anthracis str. Ames

Type:

Genome variation profiling by array

Platform:

GPL370

3 Samples

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