GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Rhodotorula; Bos taurus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus; Quercus alba; Trypanosoma cruzi; Bothrops moojeni; Pachymenia carnosa; Gallus gallus; Oryctolagus cuniculus; Mus musculus; Human immunodeficiency virus 1; unidentified; Megathura crenulata

Type:

Protein profiling by protein array

Platforms:

GPL23566 GPL23565

55 Samples

Download data: GPR

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Trypanosoma cruzi; Gallus gallus; Pachymenia carnosa; Ovis aries; Oryctolagus cuniculus; Megathura crenulata; Frangula alnus; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Quercus alba; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Dermestes lardarius

Type:

Protein profiling by protein array

Platform:

GPL23566

7 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:

Protein profiling by protein array

Platform:

GPL23566

7 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Rhodotorula; Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Quercus alba; Gossypium hirsutum; Oryctolagus cuniculus; Megathura crenulata; Homo sapiens; Bos taurus; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:

Protein profiling by protein array

Platform:

GPL23566

7 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Rhodotorula; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Trypanosoma cruzi; Bos taurus; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus

Type:

Protein profiling by protein array

Platform:

GPL23566

7 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:

Protein profiling by protein array

Platform:

GPL23566

7 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Quercus alba; Gossypium hirsutum; Oncorhynchus nerka; Rhodotorula; Trypanosoma cruzi; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Homo sapiens; Bos taurus; Pandalus borealis; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Dermestes lardarius

Type:

Protein profiling by protein array

Platform:

GPL23566

14 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:

Rhodotorula; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus; Trypanosoma cruzi; Gallus gallus; Ovis aries; Oryctolagus cuniculus; unidentified; Megathura crenulata; Frangula alnus

Type:

Protein profiling by protein array

Platform:

GPL23565

6 Samples

Download data: GPR, TXT

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to profile anti-glycan immune responses to whole-cell vaccines: GVAX Pancreas, K562-GM and H1299. The aim was to indentify anti-glycan antibody responses relevent to patient clinical outcomes Results: Immune responses to non-human antigens bovine fetuin and alpha-Gal antigens were identified induced by GVAX Pancreas. The magnitude of these responses inversely correlate with patient survival. more...

Organism:

Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Gossypium hirsutum; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1

Type:

Other

Platform:

GPL21991

168 Samples

Download data: GPR, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Quercus alba; Megathura crenulata; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:

Other

Platforms:

GPL20117 GPL20116

331 Samples

Download data

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to develop a novel method to assign ABO blood type. The method will then be applied to samples from patients treated with PROSTVAC to determine if blood type correlates with survival Results: Many blood group A and B antigens correlate with blood type. Blood typing is best achieved using a combination of 10 signals Conclusion: ABO blood type can be determined with greater than 97% accuracy using only 4 microliters of serum.

Organism:

Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Trypanosoma cruzi; Bos taurus; Gallus gallus; Ovis aries; Ceratonia siliqua; Megathura crenulata; Frangula alnus

Type:

Other

Platform:

GPL20116

220 Samples

Download data: TXT

(Submitter supplied) To characterise the transcriptional response in brain of Sockeye Salmon (Oncorhynchus nerka) that were persistently infected with infectious hematopoietic necrosis virus (IHNV) and to determine whether carrying the IHNV affects the ability to respond to other immunological challenges we compared the brain transcriptome of IHNV carriers, IHNV-negative survivors, and naïve Sockeye Salmon that were never exposed to IHNV. more...

Organism:

Oncorhynchus nerka; Salmo salar

Type:

Expression profiling by array

Platform:

GPL11299

35 Samples

Download data: TXT

(Submitter supplied) The main findings of the current study were that exposing adult sockeye salmon Oncorhynchus nerka to a warm temperature that they regularly encounter during their river migration induced an mRNA-level heat shock response that is exacerbated with swimming. Similar immune defense-related responses were also observed. Microarray analyses revealed that 347 genes were differentially expressed between the cold (12-13° C) and warm (18-19° C) treated fish (P < 0.01), with stress response (GO:0006950; P = 0.014) and response to fungus (GO:0009620; P = 0.003) elevated with warm treatment, while expression for genes involved in oxidative phosphorylation (GO:0006119; P = 0.0019) and electron transport chain (GO:0022900; P = 0.00043) increased in cold-treated fish. more...

Organism:

Salmo salar; Oncorhynchus mykiss; Oncorhynchus nerka

Type:

Expression profiling by array

Platform:

GPL3976

8 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Salmo salar; Oncorhynchus nerka; Oncorhynchus gorbuscha

Type:

Expression profiling by array

Platform:

GPL11299

98 Samples

Download data: TXT

(Submitter supplied) Characterizing a common cellular stress response (CSR) to high water temperature across species and populations is necessary for identifying the capacity of Pacific salmon (Oncorhynchus spp.) to persist in current and future climate warming scenarios, especially for populations at the southern periphery of their species' distributions. In this study, populations of wild adult pink (O. gorbuscha) and sockeye (O. more...

Organism:

Salmo salar; Oncorhynchus nerka; Oncorhynchus gorbuscha

Type:

Expression profiling by array

Platform:

GPL11299

44 Samples

Download data: TXT

(Submitter supplied) Characterizing a common cellular stress response (CSR) to high water temperature across species and populations is necessary for identifying the capacity of Pacific salmon (Oncorhynchus spp.) to persist in current and future climate warming scenarios, especially for populations at the southern periphery of their species' distributions. In this study, populations of wild adult pink (O. gorbuscha) and sockeye (O. more...

Organism:

Oncorhynchus nerka; Salmo salar; Oncorhynchus gorbuscha

Type:

Expression profiling by array

Platform:

GPL11299

33 Samples

Download data: TXT

(Submitter supplied) Characterizing a common cellular stress response (CSR) to high water temperature across species and populations is necessary for identifying the capacity of Pacific salmon (Oncorhynchus spp.) to persist in current and future climate warming scenarios, especially for populations at the southern periphery of their species' distributions. In this study, populations of wild adult pink (O. gorbuscha) and sockeye (O. more...

Organism:

Oncorhynchus gorbuscha; Salmo salar; Oncorhynchus nerka

Type:

Expression profiling by array

Platform:

GPL11299

21 Samples

Download data: TXT

(Submitter supplied) This dataset was gene expression from natural sockeye salmon populations used to test the preservation of coexpression networks that were found in lake whitefish. Here is the abstract of the manuscript:Background : A functional understanding of processes involved in adaptive divergence is one of the awaiting opportunities afforded by high throughput transcriptomic technologies. Functional analysis of co-expressed genes has succeeded in the biomedical field in identifying key drivers of disease pathways. more...

Organism:

Oncorhynchus nerka; Salmo salar

Type:

Expression profiling by array

Platform:

GPL6260

49 Samples

Download data: TXT

(Submitter supplied) We collected sockeye salmon from the Fraser River, British Columbia, and held them at ecologically relevant temperatures (14C and 19C) determine the effect of elevated water temperature on cellular processes in non-lethally sampled gill tissue and blood plasma over a period of seven days that represents a significant portion of their upstream migration. Time-matched fish that died prematurely over the course of the holding study were also sampled for gill tissue and the transcriptomic responses in moribund fish were compared with surviving fish. more...

Organism:

Osmerus mordax; Oncorhynchus mykiss; Oncorhynchus nerka; Salmo salar; Oncorhynchus tshawytscha; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL2716

40 Samples

Download data: TXT

(Submitter supplied) We sampled lake-type and riverine sockeye in the pristine natural habitats of Aniakchak National Monument and Preserve, Alaska USA.

Organism:

Oncorhynchus nerka; Salmo salar

Type:

Expression profiling by array

Platform:

GPL6260

30 Samples

Download data: TXT