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lrrtm4l1 leucine rich repeat transmembrane neuronal 4 like 1 [ Danio rerio (zebrafish) ]

Gene ID: 100000724, updated on 4-Jan-2025

Summary

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Official Symbol
lrrtm4l1provided by ZNC
Official Full Name
leucine rich repeat transmembrane neuronal 4 like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-080327-15
See related
AllianceGenome:ZFIN:ZDB-GENE-080327-15
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sc:d0341
Summary
Enables identical protein binding activity. Predicted to be located in membrane. Is expressed in brain; central nervous system; and retina. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See lrrtm4l1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (19310345..19395745)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (19352932..19437834)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 230a Neighboring gene immunoglobulin superfamily, member 9a Neighboring gene si:ch211-127i16.2 Neighboring gene uncharacterized LOC108191473 Neighboring gene uncharacterized LOC137496578 Neighboring gene V-set and immunoglobulin domain containing 8a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. An environmentally relevant mixture of polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) disrupts mitochondrial function, lipid metabolism and neurotransmission in the brain of exposed zebrafish and their unexposed F2 offspring. Blanc M, et al. Sci Total Environ, 2021 Feb 1. PMID 32911150
  2. A cell surface interaction network of neural leucine-rich repeat receptors. Söllner C, et al. Genome Biol, 2009. PMID 19765300, Free PMC Article
  3. The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm. Panza P, et al. Neural Dev, 2015 Oct 22. PMID 26492970, Free PMC Article
  4. Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling. Martin S, et al. Mol Cell Proteomics, 2010 Dec. PMID 20802085, Free PMC Article
  5. The impact of gene expression regulation on evolution of extracellular signaling pathways. Charoensawan V, et al. Mol Cell Proteomics, 2010 Dec. PMID 20935258, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
leucine rich repeat transmembrane neuronal 4 like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386662.1 → NP_001373591.1  leucine rich repeat transmembrane neuronal 4 like 1 precursor

    Status: VALIDATED

    Source sequence(s)
    BX005125, BX293550
    UniProtKB/TrEMBL
    A0A8M1Q7K6, A0A8M3B365
    Conserved Domains (3) summary
    sd00033
    Location:60 → 83
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106 → 166
    LRR_8; Leucine rich repeat
    cd21340
    Location:153 → 308
    PPP1R42; protein phosphatase 1 regulatory subunit 42

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    19310345..19395745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479313.2 → XP_021334988.1  leucine rich repeat transmembrane neuronal 4 like 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M3B365, A0A8M9Q6F1
    Conserved Domains (2) summary
    sd00033
    Location:60 → 83
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106 → 166
    LRR_8; Leucine rich repeat

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394777.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    23532..24851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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