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nrip1b nuclear receptor interacting protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 100001853, updated on 4-Jan-2025

Summary

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Official Symbol
nrip1bprovided by ZNC
Official Full Name
nuclear receptor interacting protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4173
See related
Ensembl:ENSDARG00000068894 AllianceGenome:ZFIN:ZDB-GENE-030131-4173
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc76h12; wu:fc76h12
Summary
Predicted to enable signaling receptor binding activity and transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including hypochord; immature eye; mesoderm; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in CAKUT and osteoporosis. Orthologous to human NRIP1 (nuclear receptor interacting protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See nrip1b in Genome Data Viewer
Location:
chromosome: 10
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (38256650..38316157, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (38315347..38372409, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene microRNA 99-2 Neighboring gene ubiquitin specific peptidase 25 Neighboring gene SAM domain, SH3 domain and nuclear localisation signals 1b Neighboring gene glycerophosphodiester phosphodiesterase domain containing 5a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Feng L, et al. Dev Biol, 2010 Feb 1. PMID 19874812, Free PMC Article
  2. Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. Bertrand S, et al. PLoS Genet, 2007 Nov. PMID 17997606, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nuclear receptor-interacting protein 1
Names
RIP140-B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    38256650..38316157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169195.5 → XP_005169252.1  nuclear receptor-interacting protein 1

    UniProtKB/TrEMBL
    A0A8M2BGF6, F1QVR4, F8W2C1
    Related
    ENSDARP00000124782.1, ENSDART00000149580.2
    Conserved Domains (2) summary
    pfam15687
    Location:27 → 325
    NRIP1_repr_1; Nuclear receptor-interacting protein 1 repression 1
    pfam15688
    Location:402 → 702
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2

  2. XM_021479444.2 → XP_021335119.1  nuclear receptor-interacting protein 1

    UniProtKB/TrEMBL
    A0A8M2BGF6, F1QVR4, F8W2C1
    Conserved Domains (2) summary
    pfam15687
    Location:27 → 325
    NRIP1_repr_1; Nuclear receptor-interacting protein 1 repression 1
    pfam15688
    Location:402 → 702
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
Nucleotide Protein Strain
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