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znf292a zinc finger protein 292a [ Danio rerio (zebrafish) ]

Gene ID: 100002269, updated on 4-Jan-2025

Summary

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Official Symbol
znf292aprovided by ZNC
Official Full Name
zinc finger protein 292aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071004-18
See related
Ensembl:ENSDARG00000016763 AllianceGenome:ZFIN:ZDB-GENE-071004-18
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:171671
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human ZNF292 (zinc finger protein 292). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See znf292a in Genome Data Viewer
Location:
chromosome: 17
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (49414519..49438911, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (49331864..49355936, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene glutathione peroxidase 2 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b Neighboring gene glycoprotein hormones alpha chain-like Neighboring gene glycoprotein hormones, alpha polypeptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC171671

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 292a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105141.2 → NP_001098611.2  zinc finger protein 292a

    Status: VALIDATED

    Source sequence(s)
    CU896650
    UniProtKB/TrEMBL
    A0A8M1NFW7, E7FBU0
    Related
    ENSDARP00000005233.7, ENSDART00000004424.10
    Conserved Domains (2) summary
    COG5189
    Location:1383 → 1623
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:670 → 692
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    49414519..49438911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169874.5 → XP_005169931.1  zinc finger protein 292a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BH60
    Conserved Domains (2) summary
    COG5189
    Location:1336 → 1576
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:623 → 645
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version

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